ArticleGenome medicine2009
Race and ancestry in biomedical research: exploring the challenges.
Article in Genome medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- Attitudes and beliefs regarding race-targeted genetic testing of Black people: A systematic review.Journal of genetic counseling · 2023Pooled it
- Reporting and Analyzing Race and Ethnicity in Orthopaedic Clinical Trials: A Systematic Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021Pooled it
- The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review.PloS one · 2016Pooled it
- A data model for population descriptors in genomic research.American journal of human genetics · 2025Review
- Sociodemographic inequities in overall survival among younger and older women with cervical cancer.Cancer causes & control : CCC · 2025Article
- The Social Construction of Categorical Data: Mixed Methods Approach to Assessing Data Features in Publicly Available Datasets.JMIR medical informatics · 2025Article
- Diversity of Research Participant Gender, Race, and Ethnicity in Communication Sciences and Disorders: A Systematic Review and Quantitative Synthesis of American Speech-Language-Hearing Association Publications in 2020.Perspectives of the ASHA special interest groups · 2024Article
- Tubal Sterilization and Cervical Cancer Underscreening in the United States.Journal of women's health (2002) · 2024Article
- Aspiring toward equitable benefits from genomic advances to individuals of ancestrally diverse backgrounds.American journal of human genetics · 2024Review
- Psychological Burden of Systemic Racism-Related Distress in New York City Healthcare Workers During the COVID-19 Pandemic.Journal of general internal medicine · 2024Article
- Race and Ethnicity in Pulmonary Function Test Interpretation: An Official American Thoracic Society Statement.American journal of respiratory and critical care medicine · 2023Article
- Let's Not Repeat History's Mistakes: Two Cautions to Scientists on the Use of Race in Alzheimer's Disease and Alzheimer's Disease Related Dementias Research.Journal of Alzheimer's disease : JAD · 2023Review
- Effect of Metabolic Syndrome Risk Factors on Processing Speed and Executive Function in Three Racialized Groups.Journal of Alzheimer's disease : JAD · 2023Article
- A scoping review of guidelines for the use of race, ethnicity, and ancestry reveals widespread consensus but also points of ongoing disagreement.American journal of human genetics · 2022Article
- Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.Cell genomics · 2022Article
- Alzheimer's disease biomarkers in Black and non-Hispanic White cohorts: A contextualized review of the evidence.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Review
- Trabecular Meshwork Mitochondrial Function and Oxidative Stress: Clues to Racial Disparities of Glaucoma.Ophthalmology science · 2022Article
- Diversity's Pandemic Distractions.Health matrix (Cleveland, Ohio : 1991) · 2022Article
- Uprooting race-based assumptions in biomedical journal articles.Trends in molecular medicine · 2021Article
- Leveraging genetic ancestry to study health disparities.American journal of physical anthropology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 17 institutions in 4 countries.
Funding
Abstract
The use of race in biomedical research has, for decades, been a source of social controversy. However, recent events, such as the adoption of racially targeted pharmaceuticals, have raised the profile of the race issue. In addition, we are entering an era in which genomic research is increasingly focused on the nature and extent of human genetic variation, often examined by population, which leads to heightened potential for misunderstandings or misuse of terms concerning genetic variation and race. Here, we draw together the perspectives of participants in a recent interdisciplinary workshop on ancestry and health in medicine in order to explore the use of race in research issue from the vantage point of a variety of disciplines. We review the nature of the race controversy in the context of biomedical research and highlight several challenges to policy action, including restrictions resulting from commercial or regulatory considerations, the difficulty in presenting precise terminology in the media, and drifting or ambiguous definitions of key terms.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.