Evidence map›Paper›PMID 19347036›Full record

ArticleMathematics and computers in simulation2008

High-Resolution Models of Motion of Macromolecules in Cell Membranes.

Karin Leiderman, Stanly Steinberg

Abstract read
In one paragraph

Article in Mathematics and computers in simulation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Karin LeidermanDepartment of Mathematics and Statistics, University of New Mexico, Albuquerque NM 87131-1141 USA.
Stanly Steinberg

Funding

Signaling Activity of lgE Receptor SubunitsR01GM049814 · NIGMS · UNIVERSITY OF NEW MEXICO · PI OLIVER, JANET M. · 1993 to 2008
$2.6M
NIGMS NIH HHS R01 GM049814
6 · The paper itself

Abstract

The path of a macromolecule on a cell membrane is modeled by a sum of independent identically distributed random variables. Random variables with simple discrete distribution functions capture some important aspects of the jump or hop diffusion reported from single particle tracking experiments that measure the motion of single molecules on a cell membrane. The detail provided by the distribution function for the random variables is critical for accurate simulations of the motion and interactions of macromolecules on the cell membrane. Additionally, the probability distribution for the random variables is easily estimated from single-particle tracking data. The diffusion constant is given by the second moment of the probability distribution, which agrees with the diffusion constant estimated from the mean-square displacement, and thus represents far less information than the distribution function.

Identifiers

PMID19347036
PMCPMC2597861

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.