Evidence map›Paper›PMID 19346873›Full record

ArticleJournal of pediatric hematology/oncology2009

Highlights of the First International "Immunotherapy in Pediatric Oncology: Progress and Challenges" Meeting.

Christian M Capitini, Laurence J N Cooper, R Maarten Egeler, Rupert Handgretinger, Franco Locatelli, Paul M Sondel, Crystal L Mackall

Abstract readConference Proceedings
In one paragraph

Article in Journal of pediatric hematology/oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Immune-based therapeutics for pediatric cancer.Expert opinion on biological therapy · 2010
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian M CapitiniPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA. capitinic@mail.nih.gov
Laurence J N Cooper
R Maarten Egeler
Rupert Handgretinger
Franco Locatelli
Paul M Sondel
Crystal L Mackall

Funding

Developing Immune Based TherapiesZIABC011072 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MACKALL, CRYSTAL · 2009 to 2010
$2.6M
DIRECTING T CELL RESPONSES DURING IMMUNE RECONSTITUTIONZ01SC010281 · SC · CLINICAL SCIENCES · PI MACKALL, CRYSTAL L · 1998 to 2007
$985k
Immunobiology and Immunotherapy of Pediatric TumorsZ01SC010289 · SC · CLINICAL SCIENCES · PI MACKALL, CRYSTAL L. · 1999 to 2007
$985k
Intramural NIH HHS Z01 SC010281Intramural NIH HHS Z01 SC010289Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

The first annual conference on immunotherapy in pediatric oncology was held in Bethesda, MD, from September 9 to 10, 2008 to discuss the state-of-the-art of immunotherapeutic strategies currently being explored in pediatric oncology. Major topics included targeting cell surface receptors, understanding and improving T-cell-based therapies, augmenting innate immune strategies, and enhancing graft-versus-leukemia for pediatric malignancies. As can be seen in the summaries of the individual presentations, significant progress has been made in developing preclinical models of pediatric tumors and a variety of novel immunobiologic therapies are approaching, or already in, the clinic. Although there is much excitement about the potential utility of these agents, a great deal of challenges lie ahead in improving the efficacy of each of these modalities and getting them to patients in a timely fashion. The resulting discussions will hopefully lead to new collaborations and insight for further translational and clinical studies.

Indexed as

ChildHumansImmunotherapyInternationalityMedical OncologyNeoplasmsPediatrics

Identifiers

PMID19346873
PMCPMC2714285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.