ReviewJournal of radiation research2009
Expanding the question-answering potential of single-cell microbeams at RARAF, USA.
Review in Journal of radiation research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- A Method to Locally Irradiate Specific Organ in Model Organisms Using a Focused Heavy-Ion Microbeam.Biology · 2023Article
- The IRI-DICE hypothesis: ionizing radiation-induced DSBs may have a functional role for non-deterministic responses at low doses.Radiation and environmental biophysics · 2020Article
- Space Radiation Biology for "Living in Space".BioMed research international · 2020Review
- Focus small to find big - the microbeam story.International journal of radiation biology · 2018Review
- Automated microbeam observation environment for biological analysis-Custom portable environmental control applied to a vertical microbeam system.Sensors and actuators. B, Chemical · 2017Article
- SPICE-NIRS microbeam: a focused vertical system for proton irradiation of a single cell for radiobiological research.Journal of radiation research · 2013Article
- Optofluidic cell manipulation for a biological microbeam.The Review of scientific instruments · 2013Article
- Design of a novel flow-and-shoot microbeam.Radiation protection dosimetry · 2011Article
- Immersion Mirau interferometry for label-free live cell imaging in an epi-illumination geometry.Proceedings of SPIE--the International Society for Optical Engineering · 2010Article
- Radiation microbeams as spatial and temporal probes of subcellular and tissue response.Mutation researchReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 2 countries.
Funding
Abstract
Charged-particle microbeams, developed to provide targeted irradiation of individual cells, and then of sub-cellular components, and then of 3-D tissues and now organisms, have been instrumental in challenging and changing long accepted paradigms of radiation action. However the potential of these valuable tools can be enhanced by integrating additional components with the direct ability to measure biological responses in real time, or to manipulate the cell, tissue or organism of interest under conditions where information gained can be optimized. The RARAF microbeam has recently undergone an accelerator upgrade, and been modified to allow for multiple microbeam irradiation laboratories. Researchers with divergent interests have expressed desires for particular modalities to be made available and ongoing developments reflect these desires. The focus of this review is on the design, incorporation and use of multiphoton and other imaging, micro-manipulation and single cell biosensor capabilities at RARAF. Additionally, an update on the status of the other biology oriented microbeams in the Americas is provided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.