Evidence map›Paper›PMID 19346342›Full record

ArticleApplied and environmental microbiology2009

Molecular diversification in the quorum-sensing system of Vibrio cholerae: Role of natural selection in the emergence of pandemic strains.

Nina M Talyzina, Pär K Ingvarsson, Jun Zhu, Sun N Wai, Agneta Andersson

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Sequence Polymorphisms inApplied and environmental microbiology · 2022
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Differential RNA-seq of Vibrio cholerae identifies the VqmR small RNA as a regulator of biofilm formation.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nina M TalyzinaDepartment of Ecology and Environmental Science, Umeå University, Sweden. nina.talyzina@emg.umu.se
Pär K Ingvarsson
Jun Zhu
Sun N Wai
Agneta Andersson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two haplotypes of the Vibrio cholerae quorum-sensing system regulator hapR are described: hapR1, common among nonpandemic, non-O1, non-O139 strains, and hapR2, associated with pandemic O1 and O139 and epidemic O37 V. cholerae strains. The hapR2 has evolved under strong natural selection, implying that its fixation was influenced by conditions that led to cholera pandemics.

Indexed as

Quorum SensingSelection, GeneticBacterial ProteinsCholeraDisease OutbreaksDNA, BacterialGene Expression RegulationMolecular Sequence DataPhylogenyPolymorphism, GeneticSequence Analysis, DNAVibrio cholerae non-O1Vibrio cholerae O1Vibrio cholerae O139Bacterial ProteinsDNA, Bacterial

Identifiers

PMID19346342
PMCPMC2687267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.