ReviewTrends in cardiovascular medicine2008
Endothelium-driven myocardial growth or nitric oxide at the crossroads.
Review in Trends in cardiovascular medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Metabolic and Immune Crosstalk in Cardiovascular Disease.Circulation research · 2025Review
- Dapagliflozin prevents ERK activation and SGLT2-dependent endoglin upregulation in a mechanically provoked cardiac injury model.Physiological reports · 2024Article
- Basal Vascular Smooth Muscle Cell Tone in eNOS Knockout Mice Can Be Reversed by Cyclic Stretch and Is Independent of Age.Frontiers in physiology · 2022Article
- A multi-omics approach to identify molecular alterations in a mouse model of heart failure.Theranostics · 2022Article
- Matters of the heart: Cellular sex differences.Journal of molecular and cellular cardiology · 2021Review
- Biomarkers of Oxidative Stress in Metabolic Syndrome and Associated Diseases.Oxidative medicine and cellular longevity · 2019Review
- Mechanical Stretching Simulates Cardiac Physiology and Pathology through Mechanosensor Piezo1.Journal of clinical medicine · 2018Article
- Growth inhibition of human breast carcinoma cells by overexpression of regulator of G-protein signaling 4.Oncology letters · 2017Article
- Cardioprotective Effect ofFrontiers in pharmacology · 2016Article
- Cardiac NO signalling in the metabolic syndrome.British journal of pharmacology · 2015Review
- Elimination of vitamin D receptor in vascular endothelial cells alters vascular function.Hypertension (Dallas, Tex. : 1979) · 2014Article
- Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenance.Experimental cell research · 2013Article
- NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth.The Journal of clinical investigation · 2013Article
- Importance of myocyte-nonmyocyte interactions in cardiac development and disease.Circulation research · 2012Review
- Activation of group VI phospholipase A2 isoforms in cardiac endothelial cells.American journal of physiology. Cell physiology · 2011Article
- Cell communications in the heart.Circulation · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Endothelium lining the coronary vasculature and the heart chambers is a dynamic sensor that serves a variety of functions including bidirectional communications with cardiac myocytes. Among endothelium-released factors, nitric oxide exerts multifactorial effects on various cell types in the heart and may play a role in growth of the vasculature and myocardial hypertrophy. This review summarizes new data regarding the endothelium-to-myocyte signaling focusing on its role in regulation of cardiac hypertrophy through a nitric-oxide-mediated paracrine signal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.