ReviewBiochimica et biophysica acta2009
Soft materials to treat central nervous system injuries: evaluation of the suitability of non-mammalian fibrin gels.
Review in Biochimica et biophysica acta, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Message in a Scaffold: Natural Biomaterials for Three-Dimensional (3D) Bioprinting of Human Brain Organoids.Biomolecules · 2022Review
- Growth of MIN-6 Cells on Salmon Fibrinogen Scaffold Improves Insulin Secretion.Pharmaceutics · 2022Article
- Building a Functional Salivary Gland for Cell-Based Therapy: More than Secretory Epithelial Acini.Tissue engineering. Part A · 2020Review
- Salmon fibrinogen and chitosan scaffold for tissue engineering: in vitro and in vivo evaluation.Journal of materials science. Materials in medicine · 2018Article
- Human cathepsins K, L, and S: Related proteases, but unique fibrinolytic activity.Biochimica et biophysica acta. General subjects · 2018Article
- Fibrin-Enhanced Canonical Wnt Signaling Directs Plasminogen Expression in Cementoblasts.International journal of molecular sciences · 2017Article
- CRISPR/Cas9-Mediated Genome Editing Corrects Dystrophin Mutation in Skeletal Muscle Stem Cells in a Mouse Model of Muscle Dystrophy.Molecular therapy. Nucleic acids · 2017Article
- Selective Expansion of Skeletal Muscle Stem Cells from Bulk Muscle Cells in Soft Three-Dimensional Fibrin Gel.Stem cells translational medicine · 2017Article
- Combination scaffolds of salmon fibrin, hyaluronic acid, and laminin for human neural stem cell and vascular tissue engineering.Acta biomaterialia · 2016Article
- Myelinating glia differentiation is regulated by extracellular matrix elasticity.Scientific reports · 2016Article
- Salmon-derived thrombin inhibits development of chronic pain through an endothelial barrier protective mechanism dependent on APC.Biomaterials · 2016Article
- AAVshRNA-mediated suppression of PTEN in adult rats in combination with salmon fibrin administration enables regenerative growth of corticospinal axons and enhances recovery of voluntary motor function after cervical spinal cord injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Article
- Soft fibrin gels promote selection and growth of tumorigenic cells.Nature materials · 2012Article
- Salmon fibrin treatment of spinal cord injury promotes functional recovery and density of serotonergic innervation.Experimental neurology · 2012Article
- Novel magnetic fibrin hydrogel scaffolds containing thrombin and growth factors conjugated iron oxide nanoparticles for tissue engineering.International journal of nanomedicine · 2012Article
- The potential for salmon fibrin and thrombin to mitigate pain subsequent to cervical nerve root injury.Biomaterials · 2011Article
- Rho GTPases mediate the mechanosensitive lineage commitment of neural stem cells.Stem cells (Dayton, Ohio) · 2011Article
- A novel double-targeted nondrug delivery system for targeting cancer stem cells.International journal of nanomedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Polymeric scaffolds formed from synthetic or natural materials have many applications in tissue engineering and medicine, and multiple material properties need to be optimized for specific applications. Recent studies have emphasized the importance of the scaffolds' mechanical properties to support specific cellular responses in addition to considerations of biochemical interactions, material transport, immunogenicity, and other factors that determine biocompatibility. Fibrin gels formed from purified fibrinogen and thrombin, the final two reactants in the blood coagulation cascade, have long been shown to be effective in wound healing and supporting the growth of cells in vitro and in vivo. Fibrin, even without additional growth factors or other components has potential for use in neuronal wound healing in part because of its mechanical compliance that supports the growth of neurons without activation of glial proliferation. This review summarizes issues related to the use of fibrin gels in neuronal cell contexts, with an emphasis on issues of immunogenicity, and considers the potential advantages and disadvantages of fibrin prepared from non-mammalian sources.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.