Evidence map›Paper›PMID 19343684›Full record

ArticleJournal of biophotonics2009

Spectral detection of micro-metastases in lymph node histo-pathology.

Benjamin Bird, Melissa Romeo, Nora Laver, Max Diem

Abstract readEvaluation Study
In one paragraph

Article in Journal of biophotonics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benjamin BirdLaboratory for Spectral Diagnosis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.
Melissa Romeo
Nora Laver
Max Diem

Funding

Detection of Cancer in Lymph Nodes by Spectral ImagingR01CA111330 · NCI · NORTHEASTERN UNIVERSITY · PI DIEM, MAX · 2005 to 2007
$1.0M
NCI NIH HHS CA 111330NCI NIH HHS R01 CA111330
6 · The paper itself

Abstract

The first detection of breast cancer micrometastases in lymph nodes by infrared spectral imaging and methods of multivariate analysis is reported. Micrometastases are indicators of early spread of cancer from the organ originally affected by disease, and their detection is of prime importance for the staging and treatment of cancer. Infrared spectral imaging, at a spatial resolution of ca. 10-12 mum, can detect small metastases down to the level of a few cancerous cells. The results presented here add to a rapidly growing database of infrared spectral imaging results for cancer diagnostics.

Indexed as

Breast NeoplasmsData Interpretation, StatisticalFemaleHistological TechniquesHumansImage Interpretation, Computer-AssistedLymphatic MetastasisSpectrophotometry, Infrared

Identifiers

PMID19343684
PMCPMC2753368

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.