ReviewGenetica2009
The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans.
Review in Genetica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Light and Shadows: Insights from Large-Scale Visual Screens for Arabidopsis Leaf Morphology Mutants.International journal of molecular sciences · 2025Review
- Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation.PLoS genetics · 2024Article
- TheGenetics · 2019Review
- An SMC-like protein binds and regulates Caenorhabditis elegans condensins.PLoS genetics · 2017Article
- Targeted genome engineering inCell & bioscience · 2016Review
- Article
- The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling.Nucleic acids research · 2015Article
- ITIS, a bioinformatics tool for accurate identification of transposon insertion sites using next-generation sequencing data.BMC bioinformatics · 2015Article
- Forward and reverse mutagenesis in C. elegans.WormBook : the online review of C. elegans biology · 2014Review
- Exciting prospects for precise engineering of Caenorhabditis elegans genomes with CRISPR/Cas9.Genetics · 2013Review
- Metal-induced neurodegeneration in C. elegans.Frontiers in aging neuroscience · 2013Article
- A genome-wide collection of Mos1 transposon insertion mutants for the C. elegans research community.PloS one · 2012Article
- The early bird catches the worm: new technologies for the Caenorhabditis elegans toolkit.Nature reviews. Genetics · 2011Review
- The Drosophila gene disruption project: progress using transposons with distinctive site specificities.Genetics · 2011Article
- Selectable genetic markers for nematode transgenesis.Cellular and molecular life sciences : CMLS · 2011Review
- Imaging C. elegans embryos using an epifluorescent microscope and open source software.Journal of visualized experiments : JoVE · 2011Article
- MosSCI and gateway compatible plasmid toolkit for constitutive and inducible expression of transgenes in the C. elegans germline.PloS one · 2011Article
- Reverse genetics in eukaryotes.Biology of the cell · 2010Review
- An antibiotic selection marker for nematode transgenesis.Nature methods · 2010Article
- Transposon-based screens for cancer gene discovery in mouse models.Seminars in cancer biology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nematode Caenorhabditis elegans is a widely appreciated, powerful platform in which to study important biological mechanisms related to human health. More than 65% of human disease genes have homologues in the C. elegans genome, and essential aspects of mammalian cell biology, neurobiology and development are faithfully recapitulated in this organism. The EU-funded NemaGENETAG project was initiated with the aim to develop cutting-edge tools and resources that will facilitate modelling of human pathologies in C. elegans, and advance our understanding of animal development and physiology. The main objective of the project involves the generation and evaluation of a large collection of transposon-tagged mutants. In the process of achieving this objective the NemaGENETAG consortium also endeavours to optimize and automate existing transposon-mediated mutagenesis methodologies based on the Mos1 transposable element, in addition to developing alternatives using other transposon systems. The final product of this initiative-a comprehensive collection of transposon-tagged alleles-together with the acquisition of efficient transposon-based tools for mutagenesis and transgenesis in C. elegans, should yield a wealth of information on gene function, immediately relevant to key biological processes and to pharmaceutical research and development.
Indexed as
Identifiers
19343510What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.