Evidence map›Paper›PMID 19339488›Full record

ArticleClinical and vaccine immunology : CVI2009

Cellular and humoral responses to Leishmania major virulence factors in healed cutaneous leishmaniasis and Mediterranean visceral leishmaniasis patients.

Inès Lakhal-Naouar, Thouraya Boussoffara, Amel Meddeb-Garnaoui, Yosser Ben Achour-Chenik, Hechmi Louzir, Mehdi Chenik

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Viruses · 2021
    Article
  2. Article
  3. A current perspective on leishmaniasis.Journal of global infectious diseases · 2010
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Inès Lakhal-NaouarInstitut Pasteur de Tunis, BP 74, 13, Place Pasteur, 1002 Tunis, Tunisia. mehdi.chenik@pasteur.rns.tn.
Thouraya Boussoffara
Amel Meddeb-Garnaoui
Yosser Ben Achour-Chenik
Hechmi Louzir
Mehdi Chenik
Institut Pasteur de Tunis · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular and humoral immune responses of healed cutaneous leishmaniasis and Mediterranean visceral leishmaniasis patients were evaluated against results for Leishmania major virulence proteins L. major protein disulfide isomerase (LmPDI) and mitogen-activated protein kinase kinase (MAPKK). Only MAPKK induces significant peripheral blood mononuclear cell proliferation with gamma interferon production as well as antibody responses. Thus, MAPKK may be of interest in Leishmania vaccination and serodiagnosis.

Indexed as

AdolescentAdultAnimalsAntibodies, ProtozoanCell ProliferationCells, CulturedChild, PreschoolHumansInfantInterferon-gammaLeishmania majorLeishmaniasis, CutaneousLeishmaniasis, VisceralLeukocytes, MononuclearMitogen-Activated Protein Kinase KinasesProtein Disulfide-IsomerasesAntibodies, ProtozoanInterferon-gammaMitogen-Activated Protein Kinase KinasesProtein Disulfide-IsomerasesProtozoan ProteinsVirulence Factors

Identifiers

PMID19339488
PMCPMC2691049
OpenAlexW2103948525

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.