Evidence map›Paper›PMID 19339173›Full record

ReviewCurrent opinion in structural biology2009

Hybrid approaches: applying computational methods in cryo-electron microscopy.

Steffen Lindert, Phoebe L Stewart, Jens Meiler

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. [Progress in filters for denoising cryo-electron microscopy images].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Modeling protein assemblies in the proteome.Molecular & cellular proteomics : MCP · 2014
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Conventions and workflows for using Situs.Acta crystallographica. Section D, Biological crystallography · 2012
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Steffen LindertDepartment of Chemistry, Vanderbilt University, Nashville, TN 37212, USA.
Phoebe L Stewart
Jens Meiler

Funding

Membrane Protein Structure Elucidation from sparse NMR data (KAMP)R01GM080403 · NIGMS · VANDERBILT UNIVERSITY · PI MEILER, JENS · 2007 to 2019
$3.0M
Cryo-EM Structural Studies of Adenovirus Cell EntryR01AI042929 · NIAID · VANDERBILT UNIVERSITY · PI STEWART, PHOEBE L · 2004 to 2010
$2.8M
NIAID NIH HHS R01 AI042929NIAID NIH HHS R01 AI 42929NIGMS NIH HHS R01 GM 080403NIGMS NIH HHS R01 GM080403
6 · The paper itself

Abstract

Recent advances in cryo-electron microscopy have led to an increasing number of high (3-5A) to medium (5-10A) resolution cryoEM density maps. These density maps contain valuable information about the protein structure but frequently require computational algorithms to aid their structural interpretation. It is these hybrid approaches between cryoEM and computational protein structure prediction algorithms that will shape protein structure elucidation from density maps.

Indexed as

AlgorithmsProtein ConformationComputational BiologyCryoelectron MicroscopyImaging, Three-DimensionalModels, MolecularProtein FoldingProteinsProtein Structure, SecondarySoftwareProteins

Identifiers

PMID19339173
PMCPMC2726835

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.