ArticleTherapeutics and clinical risk management2008
Effects of treatment with antimicrobial agents on the human colonic microflora.
Article in Therapeutics and clinical risk management, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of antibiotics on growth in children in low and middle income countries: systematic review and meta-analysis of randomised controlled trials.BMJ (Clinical research ed.) · 2014Pooled it
- Biannual azithromycin distribution and child mortality among malnourished children: A subgroup analysis of the MORDOR cluster-randomized trial in Niger.PLoS medicine · 2020Trial
- Equol production changes over time in postmenopausal women.The Journal of nutritional biochemistry · 2012Trial
- In Vitro Activity of Bacteriophages Against Ocular Methicillin-resistant S. aureus Isolates Collected in the US.Ophthalmology and therapy · 2025Article
- Gut-Antimicrobial Peptides: Synergistic Co-Evolution with Antibiotics to Combat Multi-Antibiotic Resistance.Antibiotics (Basel, Switzerland) · 2023Review
- Gut microbiota and its diet-related activity in children with intestinal failure receiving long-term parenteral nutrition.JPEN. Journal of parenteral and enteral nutrition · 2022Article
- Antidiarrheal and Antisecretory Effect of 80% Hydromethanolic Leaf Extract ofBiochemistry research international · 2022Article
- Mathematically modeling the effect of touch frequency on the environmental transmission of Clostridioides difficile in healthcare settings.Mathematical biosciences · 2021Article
- Article
- Effects of prophylactic and therapeutic antimicrobial uses in small-scale chicken flocks.Zoonoses and public health · 2021Article
- Genetic and Chemical Engineering of Phages for Controlling Multidrug-Resistant Bacteria.Antibiotics (Basel, Switzerland) · 2021Review
- Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy.Toxicology reports · 2021Review
- Hospital-based ciprofloxacin use evaluation in Eastern Ethiopia: a retrospective assessment of clinical practice.The Pan African medical journal · 2021Article
- Ultrapotent Inhibitor ofJournal of medicinal chemistry · 2020Article
- Consumption of a Western-Style Diet Modulates the Response of the Murine Gut Microbiome to Ciprofloxacin.mSystems · 2020Article
- Fidaxomicin for the treatment ofFuture microbiology · 2020Article
- Article
- Efficient Early Diagnosis of Sepsis Using Whole-Blood PCR-Reverse Blot Hybridization Assay Depending on Serum Procalcitonin Levels.Frontiers in medicine · 2020Article
- The effect of diet on the gastrointestinal microbiome of juvenile rehabilitating green turtles (Chelonia mydas).PloS one · 2020Article
- Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome.Cell metabolism · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial agents are the most valuable means available for treating bacterial infections. However, the administration of therapeutic doses of antimicrobial agents to patients is a leading cause of disturbance of the normal gastrointestinal microflora. This disturbance results in diminishing the natural defense mechanisms provided by the colonic microbial ecosystem, making the host vulnerable to infection by commensal microorganisms or nosocomial pathogens. In this minireview, the impacts of antimicrobials, individually and in combinations, on the human colonic microflora are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.