ArticlePloS one2009
The viscoelastic properties of passive eye muscle in primates. I: static forces and step responses.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Novel System for Measuring Tension Force in Eyeball Movement.Biosensors · 2025Article
- Structure-Function relationships in the skeletal muscle extracellular matrix.Journal of biomechanics · 2023Review
- Oculomotor plant and neural dynamics suggest gaze control requires integration on distributed timescales.The Journal of physiology · 2022Article
- The biomechanical significance of pulley on binocular vision.Biomedical engineering online · 2016Article
- Altered Protein Composition and Gene Expression in Strabismic Human Extraocular Muscles and Tendons.Investigative ophthalmology & visual science · 2016Article
- Contractile Force of Human Extraocular Muscle: A Theoretical Analysis.Applied bionics and biomechanics · 2016Article
- Mechanics of mouse ocular motor plant quantified by optogenetic techniques.Journal of neurophysiology · 2015Article
- Atomic force microscopy determination of Young׳s modulus of bovine extra-ocular tendon fiber bundles.Journal of biomechanics · 2014Article
- Tests of linearity in the responses of eye-movement-sensitive vestibular neurons to sinusoidal yaw rotation.Journal of neurophysiology · 2013Article
- Determination of poisson ratio of bovine extraocular muscle by computed X-ray tomography.BioMed research international · 2013Article
- Dynamics of abducens nucleus neurons in the awake mouse.Journal of neurophysiology · 2012Article
- Components of the neural signal underlying congenital nystagmus.Experimental brain research · 2012Article
- Extraocular muscle motor units characterized by spike-triggered averaging in alert monkey.Journal of neuroscience methods · 2012Article
- A nonlinear model of passive muscle viscosity.Journal of biomechanical engineering · 2011Article
- The nonlinearity of passive extraocular muscles.Annals of the New York Academy of Sciences · 2011Article
- Characterization of ocular tissues using microindentation and hertzian viscoelastic models.Investigative ophthalmology & visual science · 2011Article
- Creep behavior of passive bovine extraocular muscle.Journal of biomedicine & biotechnology · 2011Article
- The viscoelastic properties of passive eye muscle in primates. III: force elicited by natural elongations.PloS one · 2010Article
- The viscoelastic properties of passive eye muscle in primates. II: testing the quasi-linear theory.PloS one · 2009Article
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Authors and funding
4 authors.
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Abstract
The viscoelastic properties of passive eye muscles are prime determinants of the deficits observed following eye muscle paralysis, the root cause of several types of strabismus. Our limited knowledge about such properties is hindering the ability of eye plant models to assist in formulating a patient's diagnosis and prognosis. To investigate these properties we conducted an extensive in vivo study of the mechanics of passive eye muscles in deeply anesthetized and paralyzed monkeys. We describe here the static length-tension relationship and the transient forces elicited by small step-like elongations. We found that the static force increases nonlinearly with length, as previously shown. As expected, an elongation step induces a fast rise in force, followed by a prolonged decay. The time course of the decay is however considerably more complex than previously thought, indicating the presence of several relaxation processes, with time constants ranging from 1 ms to at least 40 s. The mechanical properties of passive eye muscles are thus similar to those of many other biological passive tissues. Eye plant models, which for lack of data had to rely on (erroneous) assumptions, will have to be updated to incorporate these properties.
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