ReviewNature cell biology2009
Spindle orientation during asymmetric cell division.
Review in Nature cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 274 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
274 citing papers in PubMed.
- USP21-mediated deubiquitylation stimulates NuMA recruitment to the cell cortex to promote mitotic spindle orientation.Cell death and differentiation · 2026Article
- Zebrafish otic vesicle and mouse epididymis as model systems for studying columnar epithelial cell division.Scientific reports · 2026Article
- Oriented cell divisions induce basal progenitors and regulate neural expansion across tissues and species.Science advances · 2026Article
- Zebrafish otic vesicle and mouse epididymis as model systems for studying columnar epithelial cell division.bioRxiv : the preprint server for biology · 2025Article
- Dual mitotic bookmarking by GAF and H3K27ac orchestrates differential propagation of cell fate memory in neural development.Nature communications · 2025Article
- Microtubule-Targeting Agents: Advances in Tubulin Binding and Small Molecule Therapy for Gliomas and Neurodegenerative Diseases.International journal of molecular sciences · 2025Review
- Functional Divergence ofInternational journal of molecular sciences · 2025Article
- Perturbed cell fate decision by schizophrenia-associated AS3MTScience advances · 2025Article
- Article
- Mitochondrial Dynamics in Brain Cells During Normal and Pathological Aging.International journal of molecular sciences · 2024Review
- On the origin of mitosis-derived human embryo aneuploidy.Nature communications · 2024Article
- Sirtuin 5-driven meiotic spindle assembly and actin-based migration in mouse oocyte meiosis.Heliyon · 2024Article
- Imaging and Analysis of Drosophila Neural Stem Cell Asymmetric Division.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Protein phase separation: new insights into cell division.Acta biochimica et biophysica Sinica · 2023Article
- The Drosophila mitotic spindle orientation machinery requires activation, not just localization.EMBO reports · 2023Article
- Spatio-Temporal Expression Pattern of CAKUT Candidate GenesBiomolecules · 2023Article
- Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes.Cell & bioscience · 2022Article
- Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way.PLoS biology · 2022Article
- Stochastic model of T cell repolarization during target elimination (II).Biophysical journal · 2022Article
- LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland.Cell reports · 2022Article
214 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Development of a multicellular organism from a fertilized egg depends on a precise balance between symmetric cell divisions to expand the pool of similar cells, and asymmetric cell divisions to create cell-type diversity. Spindle orientation can influence the generation of symmetric or asymmetric cell fates depending on how it is coupled to cell-intrinsic polarity cues, or how it is positioned relative to cell-extrinsic cues such as niche-derived signals. In this review, we describe the mechanism of spindle orientation in budding yeast, Drosophila melanogaster, Caenorhabditis elegans and mammalian neural progenitors, with the goal of highlighting conserved mechanisms and indicating open questions for the future.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.