ArticleJournal of endocrinological investigation2009
Salivary free insulin-like growth factor-i levels: effects of an acute physical exercise in athletes.
Article in Journal of endocrinological investigation, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Effects of high-intensity interval training on executive functions and IGF-1 levels in sedentary young women: a randomized controlled trial.Frontiers in sports and active living · 2025Article
- The Effects of Physical Exercise on Saliva Composition: A Comprehensive Review.Dentistry journal · 2022Review
- Elevated serum insulin-like growth factor 1 in recurrent aphthous stomatitis.Clinical and experimental dental research · 2019Article
- Effects of acute exercise on salivary free insulin-like growth factor 1 and interleukin 10 in sportsmen.African health sciences · 2016Article
- IGF-I/IGFBP system: metabolism outline and physical exercise.Journal of endocrinological investigation · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsThe offer of human saliva IGF-I (sIGF-I) measurement in athletes investigation is a new proposal. The aim was to investigate the physical exercise effect on sIGF-I and explore plasma free IGF-I relation. MATERIALS AND
methodsSaliva and blood were collected from well-trained athletes, investigated immediately before and at the end of a physical exercise test.
resultssIGF-I was significantly increased at the end of the physical exercise. The plasma free IGF-I concentrations did not demonstrate any difference. The saliva total protein level (sTP) was also significantly increased. A positive correlation between sTP and sIGF-I, was observed, both before and after physical exercise, and between salivary and plasma free IGF-I only after physical exercise. The salivary free IGF-I level significantly increased after physical exercise, moreover a correlation with the plasma levels exists in post-exercise condition.
conclusionThe physical exercise affects sIGF-I as well as the sTP. The correlation between plasma and salivary free IGF-I levels only in post-exercise condition suggests further studies to investigate the effects of different type and duration of physical exercise. The comparison with other salivary biochemical parameter investigation would also further increase comprehension on the role of salivary IGF-I.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.