Evidence map›Paper›PMID 19336410›Full record

ArticleNucleic acids research2009

Transcription regulation of restriction-modification system Esp1396I.

Ekaterina Bogdanova, Marina Zakharova, Simon Streeter, James E N Taylor, Tomasz Heyduk, Geoff Kneale, Konstantin Severinov

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 35 citations in OpenAlex.

  1. How to Unmask an Unknown: The Restriction-Modification SystemInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. From biophysics to 'omics and systems biology.European biophysics journal : EBJ · 2019
    Review
  11. Article
  12. Article
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  14. Article
  15. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ekaterina BogdanovaWaksman Institute for Microbiology, Department of Biochemistry and Molecular Biology, Rutgers, State University of New Jersey, Piscataway, NJ 08854, USA.
Marina Zakharova
Simon Streeter
James E N Taylor
Tomasz Heyduk
Geoff Kneale
Konstantin Severinov
Rutgers, The State University of New Jersey · USG. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms · RURussian Academy of Sciences · RU

Funding

Phage-induced modifications of RNA polymeraseR01GM059295 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SEVERINOV, KONSTANTIN V · 1999 to 2013
$4.5M
Regulation of restriction-modification genes expressionR03TW007145 · FIC · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI SEVERINOV, KONSTANTIN V · 2005 to 2007
$105k
Biotechnology and Biological Sciences Research Council B20404Biotechnology and Biological Sciences Research Council BB/E000878/1FIC NIH HHS R03 TW07145NIGMS NIH HHS R01 GM59295
6 · The paper itself

Abstract

The convergently transcribed restriction (R) and methylase (M) genes of the Restriction-Modification system Esp1396I are tightly regulated by a controller (C) protein that forms part of the CR operon. We have mapped the transcriptional start sites from each promoter and examined the regulatory role of C.Esp1396I

Indexed as

Gene Expression Regulation, BacterialTranscription, GeneticBacterial ProteinsBase SequenceBinding SitesDNA Modification MethylasesDNA Restriction EnzymesDNA Restriction-Modification EnzymesMolecular Sequence DataMutationPromoter Regions, GeneticTranscription FactorsTranscription Initiation SiteBacterial ProteinsDNA Modification MethylasesDNA Restriction EnzymesDNA Restriction-Modification EnzymesTranscription Factors

Identifiers

PMID19336410
PMCPMC2691842
OpenAlexW4319292966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.