ArticleContemporary clinical trials2009
A non-inferiority test of areas under two parametric ROC curves.
Article in Contemporary clinical trials, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Roadmapping stroke healthcare in Colombia: a comprehensive telestroke network evaluation.BMC medical informatics and decision making · 2026Article
- Automated ASPECTS Segmentation and Scoring Tool: a Method Tailored for a Colombian Telestroke Network.Journal of imaging informatics in medicine · 2025Article
- Bi-parametric magnetic resonance imaging based radiomics for the identification of benign and malignant prostate lesions: cross-vendor validation.Physical and engineering sciences in medicine · 2021Article
- Diagnostic and prognostic value of baseline FDG PET/CT skeletal textural features in diffuse large B cell lymphoma.European journal of nuclear medicine and molecular imaging · 2018Article
- Ruling Out Brain CT Contraindications prior to Intravenous Thrombolysis: Diagnostic Equivalence between a Primary Interpretation Workstation and a Mobile Tablet Computer.International journal of telemedicine and applications · 2017Article
- Noninferiority and Equivalence Evaluation of Clinical Performance among Computed Radiography, Film, and Digitized Film for Telemammography Services.International journal of telemedicine and applications · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Equivalence or non-inferiority in diagnostic accuracy of two medical diagnostic tests is a common medical problem. Statistical tests of non-inferiority of diagnostic tests have long been a subject of interest in medicine and biostatistical research. Accuracy of a continuous diagnostic test can be evaluated by the area under a receiver operating characteristic (ROC) curve. A conventional non-inferiority test for areas of two parametric ROC curves has been proposed by Zhou, Obuchowski, and McClish [Zhou XH, Obuchowski NA, McClish DK. Statistical Methods in Diagnostic Medicine. New York: John Wiley; 2002]. In this paper, we showed that this conventional approach is anti-conservative and proposed a new statistical test based on restricted maximum likelihood estimator to achieve designed type I error rate. Simulation studies supported this new test to be appropriate for small sample size or highly correlated diagnostic modalities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.