ArticleThe European physical journal. E, Soft matter2009
Particle tracking microrheology of gel-forming amyloid fibril networks.
Article in The European physical journal. E, Soft matter, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- A Rheological Study on the Effect of Tethering Pro- and Anti-Inflammatory Cytokines into Hydrogels on Human Mesenchymal Stem Cell Migration, Degradation, and Morphology.Biomacromolecules · 2024Article
- Characterizing Phase Transitions of Microfibrillated Cellulose Induced by Anionic and Cationic Surfactants.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Choice of Protein, Not Its Amyloid-Fold, Determines the Success of Amyloid-Based Scaffolds for Cartilage Tissue Regeneration.ACS omega · 2023Article
- Gelation phase diagrams of colloidal rod systems measured over a large composition space.RSC advances · 2022Article
- Microrheology for biomaterial design.APL bioengineering · 2020Review
- Structural Changes in Polymeric Gel Scaffolds Around the Overlap Concentration.Frontiers in chemistry · 2019Article
- Brownian motion of optically anisotropic spherical particles in polymeric suspensions.The European physical journal. E, Soft matter · 2015Article
- A microrheological study of hydrogel kinetics and micro-heterogeneity.The European physical journal. E, Soft matter · 2014Article
- High-throughput ballistic injection nanorheology to measure cell mechanics.Nature protocols · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microrheology is a technique that is increasingly used to investigate the local viscoelastic properties of complex fluids non-invasively, by tracking the motion of micron-sized probe spheres. In this work, passive Particle Tracking Microrheology (PTM) is used to study network formation in the milk protein beta-lactoglobulin at 80 degrees C and pH 2. In these conditions the protein aggregates to form thread-like structures known as amyloid fibrils, which can further aggregate into elastic networks. Using PTM, gels were observed to form at significantly lower concentrations than determined by bulk rheometry, where the oscillatory shear forces may disrupt either fibril or network formation. During incubation, the Mean Square Displacement (MSD) of the probe particles exhibited time-cure superposition, allowing the critical relaxation exponent to be calculated as approximately 0.63, consistent with other biopolymer gels. Combined with the gel-like appearance of the complex modulus at long incubation times, this confirms that a true gel is forming, with physical or chemical crosslinks forming between the fibrils, refining the conclusions of other workers in the field.
Indexed as
Identifiers
19333633What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.