SynthesisJournal of gastroenterology2009
Clinical prevention of gastric cancer by Helicobacter pylori eradication therapy: a systematic review.
Synthesis in Journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 77 citations in OpenAlex.
- Elucidating gastric cancer mechanisms and therapeutic potential of Adociaquinone A targeting EGFR: A genomic analysis and Computer Aided Drug Design (CADD) approach.Journal of cellular and molecular medicine · 2024Article
- Risk Factors Analysis and Prediction Model Establishment of Intestinal Metaplasia or Dysplasia in Patients With Chronic Atrophic Gastritis: A Multi-Center Retrospective Study.Frontiers in medicine · 2022Article
- Gastrointestinal Residue Removal Using a Balloon Overtube under Ultrathin Endoscopic Navigation: Ex Vivo and In Vivo Experimental Studies.Journal of clinical medicine · 2021Article
- Improving the Early Diagnosis of Gastric Cancer.Gastrointestinal endoscopy clinics of North America · 2021Review
- Characteristics and Early Diagnosis of Gastric Cancer Discovered afterGut and liver · 2021Review
- Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles ofGut and liver · 2020Review
- Can Natural Products Suppress ResistanteFood · 2020Article
- Changes of gastric ulcer bleeding in the metropolitan area of Japan.World journal of gastroenterology · 2019Article
- Current status of first- and second-lineTherapeutic advances in gastroenterology · 2019Article
- One-anastomosis gastric bypass as an alternative procedure of choice in morbidly obese patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018Review
- Complications Following the Mini/One Anastomosis Gastric Bypass (MGB/OAGB): a Multi-institutional Survey on 2678 Patients with a Mid-term (5 Years) Follow-up.Obesity surgery · 2017Article
- Morphological Characteristics of Early Gastric Neoplasms Detected After Helicobacter pylori Eradication.Digestive diseases and sciences · 2016Article
- Therapeutic or spontaneous Helicobacter pylori eradication can obscure magnifying narrow-band imaging of gastric tumors.Endoscopy international open · 2016Article
- Endoscopic surveillance of gastric cancers after Helicobacter pylori eradication.World journal of gastroenterology · 2015Review
- Endoscopic atrophic classification before and after H. pylori eradication is closely associated with histological atrophy and intestinal metaplasia.Endoscopy international open · 2015Article
- One thousand single anastomosis (omega loop) gastric bypasses to treat morbid obesity in a 7-year period: outcomes show few complications and good efficacy.Obesity surgery · 2015Article
- Gastric Carcinogenesis and Underlying Molecular Mechanisms: Helicobacter pylori and Novel Targeted Therapy.BioMed research international · 2015Review
- Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development.World journal of gastroenterology · 2014Review
- Enhanced expression of activation-induced cytidine deaminase in human gastric mucosa infected by Helicobacter pylori and its decrease following eradication.Journal of gastroenterology · 2014Article
- Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori (H. pylori) infection plays an important role in gastric carcinogenesis. We conducted a systematic review concerning gastric cancer development after H. pylori eradication therapy. In total 15 papers matched our criteria, the results were reviewed. The H. pylori eradication therapy statistically diminished the prevalence of clinical gastric cancer by approximately one-third. The studies from Japan supported this conclusion; however, studies from overseas reported conflicting results. The differences in these conclusions lie in the diagnostic ability of endoscopic examination, since the clinical stage was quite different between these studies. Gastric cancer that developed after eradication revealed a mainly intestinal type histology and depressed-type appearance. The following are possible reasons for reduced gastric cancer: (1) eradication therapy inhibits the new occurrence of gastric cancer, (2) eradication regresses or inhibits the growth of gastric cancer, and (3) eradication interferes with the discovery of gastric cancer. Considering the biological nature of cancer cell proliferation, a sufficiently long-term follow-up may clarify the effect of eradication therapy on inhibition of the development (not discovery) of gastric cancer and reduction of gastric cancer-related mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.