Evidence map›Paper›PMID 19332671›Full record

ArticleAntimicrobial agents and chemotherapy2009

Bacteriostatic and bactericidal activities of tigecycline against Coxiella burnetii and comparison with those of six other antibiotics.

Ioanna Spyridaki, Anna Psaroulaki, Iosif Vranakis, Yannis Tselentis, Achilleas Gikas

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Frontiers in medicine · 2025
    Article
  2. Article
  3. Epidemiology of ZoonoticMicroorganisms · 2023
    Article
  4. Review
  5. Tigecycline antibacterial activity, clinical effectiveness, and mechanisms and epidemiology of resistance: narrative review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Article
  10. Review
  11. Article
  12. Coxiella burnetii - Pathogenic Agent of Q (Query) Fever.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ioanna SpyridakiDepartment of Bacteriology, Parasitology, Zoonoses and Geographical Medicine, Faculty of Medicine, University of Crete, P.O. Box 1393, Heraklion, Crete, Greece. ispyridaki@med.uoc.gr
Anna Psaroulaki
Iosif Vranakis
Yannis Tselentis
Achilleas Gikas

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present article is a study of the in vitro susceptibility of eight Greek Coxiella burnetii isolates, derived from patients with acute Q fever, and two reference strains of Coxiella burnetii to tigecycline. The bacteriostatic activity of tigecycline was compared with those of six other antibiotics using a shell vial assay. The MICs of the examined antibiotics were as follows: tigecycline ranged from 0.25 to 0.5 microg/ml; doxycycline, trovafloxacin, and ofloxacin ranged from 1 to 2 microg/ml; linezolid and clarithromycin ranged from 2 to 4 microg/ml; and ciprofloxacin ranged from 4 to 8 microg/ml. Tigecycline was effective in inhibiting the infection of Vero cells by C. burnetii. No bactericidal activity was observed against C. burnetii at 4 microg/ml.

Indexed as

AnimalsAnti-Bacterial AgentsChlorocebus aethiopsCoxiella burnetiiHumansMicrobial Sensitivity TestsMinocyclineQ FeverTigecyclineVero CellsAnti-Bacterial AgentsMinocyclineTigecycline

Identifiers

PMID19332671
PMCPMC2687195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.