ArticleEmerging infectious diseases2009
Novel type of Streptococcus pneumoniae causing multidrug-resistant acute otitis media in children.
Article in Emerging infectious diseases, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- A new approach to define the optimal immunization strategy against pneumococcal disease: the example of Canada.Epidemiology and infection · 2025Article
- Rising Pneumococcal Antibiotic Resistance in the Post-13-Valent Pneumococcal Conjugate Vaccine Era in Pediatric Isolates From a Primary Care Setting.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Article
- Changes in Streptococcus pneumoniae serotype 19A invasive infections in children from 1993 to 2011.Journal of clinical microbiology · 2013Article
- Panel 5: Microbiology and immunology panel.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2013Review
- Nasal carriage of Streptococcus pneumoniae serotypes and Staphylococcus aureus in Streptococcus pneumoniae-vaccinated and non-vaccinated young children.Epidemiology and infection · 2013Article
- Clonality behind the increase of multidrug-resistance among non-invasive pneumococci in Southern Finland.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2012Article
- Emergence of potential superbug mycobacterium tuberculosis, lessons from new delhi mutant-1 bacterial strains.International journal of health sciences · 2012Article
- Phylogenetic relatedness and diversity of non-typable Haemophilus influenzae in the nasopharynx and middle ear fluid of children with acute otitis media.Journal of medical microbiology · 2011Article
- Population biology of Gram-positive pathogens: high-risk clones for dissemination of antibiotic resistance.FEMS microbiology reviews · 2011Review
- Streptococcus pneumoniae clonal complex 199: genetic diversity and tissue-specific virulence.PloS one · 2011Article
- Time-kill activity of the streptogramin NXL 103 against Gram-positive and -negative bacteria.Antimicrobial agents and chemotherapy · 2011Article
- Identification of Streptococcus pneumoniae and Haemophilus influenzae in culture-negative middle ear fluids from children with acute otitis media by combination of multiplex PCR and multi-locus sequencing typing.International journal of pediatric otorhinolaryngology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
After our recent discovery of a Streptococcus pneumoniae 19A "superbug" (Legacy strain) that is resistant to all Food and Drug Administration-approved antimicrobial drugs for treatment of acute otitis media (AOM) in children, other S. pneumoniae isolates from children with AOM were characterized by multilocus sequence typing (MLST). Among 40 isolates studied, 16 (40%) were serotype 19A, and 9 (23%) were resistant to multiple antimicrobial drugs. Two others had unreported sequence types (STs) that expressed the 19A capsule, and 8 (88%) of the 9 multidrug-resistant strains were serotype 19A, including the Legacy strain with the new ST-2722. In genetic relatedness, ST-2722 belonged to a cluster of reported strains of S. pneumoniae in which all strains had 6 of the same alleles as ST-156. The multidrug-resistant strains related to ST-156 expressed different capsular serotypes: 9V, 14, 11A, 15C, and 19F.
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Registered trials
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