GuidelineHepatology (Baltimore, Md.)2009
Diagnosis, management, and treatment of hepatitis C: an update.
7 registry-linked trialsOpen access · greenAbstract readPractice Guideline
In one paragraph
Guideline in Hepatology (Baltimore, Md.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 1,021 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
1,021citing papers in PubMed, 2 pooled it
107.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase 2a Study of Boceprevir for the Treatment of Genotype 6 Hepatitis C
Treatment of Chronic HCV Infected Egyptian Patients With Electromagnetic Waves and Herbal Therapy
Treatment of Chronic Hepatitis With Sofosbuvir in Combination With Ribavirin With or Without Pegylated Interferon: North India Gastroenterology Consortium
A Multicenter, Open-label Study of Harvoni ® (Sofosbuvir Ledipasvir Fixed Dose Combination) in Subjects Infected With Chronic Hepatitis C and Advanced Heart Failure or Lung Disease
Impact of Interleukin 28B (rs12979860) Genotype on Virological Responses in Chronic Hepatitis C Treatment
Changes in Hematologic Profile, Vitamin B12 and Folic Acid Level in Cirrhotic Patients Received Sofosbuvir and Daclatasvir With or Without Ribavirin
Prospective Comparison Between Transient Elastography (TE), Shear Wave Elastography (SWE) and Magnetic Resonance Elastography (MRE) for Non-invasive Assessment of Liver Fibrosis in Patients Affected by Chronic Viral Hepatitis
Who cites it
1,021 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2,966 citations in OpenAlex.
- In vitro fertilization for women infected by hepatitis C virus: a matched case-control study and a systematic literature review.Journal of assisted reproduction and genetics · 2017Pooled it
- Prevalence of hepatitis C virus infection among hemodialysis patients in the Middle-East: A systematic review and meta-analysis.World journal of gastroenterology · 2017Pooled it
- A Randomized Trial Comparing Brief Advice and Motivational Interviewing for Persons with HIV-HCV Co-infection Who Drink Alcohol.AIDS and behavior · 2021Trial
- Association of the polymorphism of the Toll-like receptor (TLR)-3 and TLR-9 genes with hepatitis C virus-specific cell-mediated immunity outcomes among Egyptian health-care workers.Clinical and experimental immunology · 2021Trial
- Glecaprevir/Pibrentasvir Treatment in Liver or Kidney Transplant Patients With Hepatitis C Virus Infection.Hepatology (Baltimore, Md.) · 2018Trial
- Efficacy and safety of sofosbuvir-based, interferon-free therapy : The Management of rheumatologic extrahepatic manifestations associated with chronic hepatitis C virus infection.Zeitschrift fur Rheumatologie · 2018Trial
- Adherence to response-guided pegylated interferon and ribavirin for people who inject drugs with hepatitis C virus genotype 2/3 infection: the ACTIVATE study.BMC infectious diseases · 2017Trial
- Use of Noninvasive Biomarker Tests vs. FibroScan for Predicting Significant Fibrosis in Egyptian Pediatric Cancer Survivors with Chronic Hepatitis C Virus Infection.Pediatric gastroenterology, hepatology & nutrition · 2026Article
- The association between antiviral therapy and 10-year overall survival of patients undergoing liver resection for hepatitis C virus- or hepatitis B virus-related hepatocellular carcinoma.Updates in surgery · 2026Article
- Sustained virological response improved survival outcomes after curative resection in patients with hepatitis C virus-related hepatocellular carcinoma in the era of direct‑acting antiviral therapy.Updates in surgery · 2026Article
- Article
- Predictors of True Early Recurrence in Patients Undergoing Radiofrequency Ablation for Hepatocellular Carcinoma.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Direct-acting antivirals for chronic hepatitis C infection: a protocol for a systematic review of observational studies.Systematic reviews · 2026Article
- 2025 KASL clinical practice guidelines for management of hepatitis C.Clinical and molecular hepatology · 2026Article
- Tumor Size Does Not Affect Survival Outcomes of Patients Undergoing Resection for a Single Hepatocellular Carcinoma Without Microscopic Vascular Invasion in the Modern Era of Antiviral Therapy.Digestive diseases and sciences · 2025Article
- Article
- A fully automated, ultrasensitive luminescence cascade sensor to address hepatitis C diagnostic disparity.Innovation (Cambridge (Mass.)) · 2025Article
- Distinct Biomarker Profiles of B-Cell Activation in Metabolic and Viral Hepatic Fibrosis.International journal of molecular sciences · 2025Article
- Getting to full disclosure: HCV testing and status disclosure behaviors among PWID and their injecting partners.BMC public health · 2025Article
- Reducing hepatitis C diagnostic disparities with a fully automated deep learning-enabled microfluidic system for HCV antigen detection.Science advances · 2025Article
961 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Marc G GhanyDepartment of Health and Human Services, Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Doris B Strader
David L Thomas
Leonard B Seeff
American Association for the Study of Liver Diseases
Johns Hopkins Medicine · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Institutes of Health · USUniversity of Vermont Medical Center · US
Funding
Natural History, Therapy and Pathogenesis of Chronic Viral Hepatitis CZIADK075009 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI GHANY, MARC · 2009 to 2025
$7.2MNatural History, Therapy and Pathogenesis of Chronic Viral Hepatitis CZ01DK075009 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI GHANY, MARC · 2008 to 2008
$378kIntramural NIH HHS Z01 DK075009
Abstract
PubMed holds no abstract for this paper.
Indexed as
BiopsyCounselingDrug UsersHepatitis CHumansInterferon-alphaInterferon alpha-2LiverLiver CirrhosisMental DisordersPolyethylene GlycolsRecombinant ProteinsRetreatmentRibavirinTreatment FailureInterferon-alphaInterferon alpha-2peginterferon alfa-2apeginterferon alfa-2bPolyethylene GlycolsRecombinant ProteinsRibavirin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT01949168ClinicalTrials.gov
NCT02215525ClinicalTrials.gov
NCT02799355ClinicalTrials.gov
NCT02858180ClinicalTrials.gov
NCT03090035ClinicalTrials.gov
NCT03283176ClinicalTrials.gov
and 1 more above
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.