Evidence map›Paper›PMID 19330467›Full record

ReviewMolecular neurobiology2009

Polarity regulation in migrating neurons in the cortex.

Orly Reiner, Tamar Sapir

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Coronin 2B Regulates Neuronal Migration via Rac1-Dependent Multipolar-Bipolar Transition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Review
  4. Neuronal Polarity: Positive and Negative Feedback Signals.Frontiers in cell and developmental biology · 2019
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. ERK2-mediated phosphorylation of Par3 regulates neuronal polarization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  16. Review
  17. Shootin1 acts in concert with KIF20B to promote polarization of migrating neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Orly ReinerDepartment of Molecular Genetics, The Weizmann Institute of Science, 76100 Rehovot, Israel. orly.reiner@weizmann.ac.il
Tamar Sapir

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formation of the cerebral cortex requires migration of billions of cells from their birth position to their final destination. A motile cell must have internal polarity in order to move in a specified direction. Locomotory polarity requires the coordinated polymerization of cytoskeletal elements such as microtubules and actin combined with regulated activities of the associated molecular motors. This review is focused on migrating neurons in the developing cerebral cortex, which need to attain internal polarity in order to reach their proper target. The position and dynamics of the centrosome plays an important function in this directed motility. We highlight recent interesting findings connecting polarity proteins with neuronal migration events regulated by the microtubule-associated molecular motor, cytoplasmic dynein.

Indexed as

Cell MovementCell PolarityAnimalsCentrosomeCerebral CortexCytoskeletal ProteinsHumansNeuronsCytoskeletal Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.