ArticlePsychiatry research2009
Regional brain volumes and symptom severity in body dysmorphic disorder.
Article in Psychiatry research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural correlates of conversion disorder: overview and meta-analysis of neuroimaging studies on motor conversion disorder.BMC psychiatry · 2016Pooled it
- Emotion regulation and visual attention in body dysmorphic disorder: a multimodal study using EEG, GSR, and eye-tracking.BMC psychiatry · 2026Article
- The Occipital-Fronto-Limbic Circuit of Body Dysmorphic Disorder: A Systematic Review and Meta-Analysis of Neuroimaging Studies.Biological psychiatry global open science · 2026Article
- Body dysmorphic disorder.Nature reviews. Disease primers · 2024Review
- Learning of the same task subserved by substantially different mechanisms between patients with body dysmorphic disorder and healthy individuals.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Cytoarchitectonically Defined Volumes of Early Extrastriate Visual Cortex in Unmedicated Adults With Body Dysmorphic Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2023Article
- Obsessive-compulsive disorder: Etiology, neuropathology, and cognitive dysfunction.Brain and behavior · 2023Review
- Deciding on Optical Illusions: Reduced Alpha Power in Body Dysmorphic Disorder.Brain sciences · 2022Article
- Neurocognitive Functioning in Young Adults with Subclinical Body Dysmorphic Disorder.The Psychiatric quarterly · 2018Article
- Visual training program for body dysmorphic disorder: protocol for a novel intervention pilot and feasibility trial.Pilot and feasibility studies · 2018Article
- Article
- Degree connectivity in body dysmorphic disorder and relationships with obsessive and compulsive symptoms.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2016Article
- Article
- Cortical thickness and brain volumetric analysis in body dysmorphic disorder.Psychiatry research · 2015Article
- Abnormalities in visual processing amongst students with body image concerns.Advances in cognitive psychology · 2014Article
- White matter microstructure in body dysmorphic disorder and its clinical correlates.Psychiatry research · 2013Article
- Body Dysmorphic Disorder: Neurobiological Features and an Updated Model.Zeitschrift fur klinische Psychologie und Psychotherapie (Gottingen, Germany) · 2013Article
- Nonlinear relationships between anxiety and visual processing of own and others' faces in body dysmorphic disorder.Psychiatry research · 2012Article
- Surgical and minimally invasive cosmetic procedures among persons with body dysmorphic disorder.Annals of plastic surgery · 2010Article
- What Causes BDD: Research Findings and a Proposed Model.Psychiatric annals · 2010Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Body dysmorphic disorder (BDD) is a severe psychiatric condition in which individuals are preoccupied with perceived defects in their appearance. Little is known of the pathophysiology or neurobiology of BDD. Recent evidence from a functional MRI study examining visual processing of faces demonstrated abnormal activation patterns in regions including left-sided inferior frontal gyrus (IFG) and amygdala. To investigate morphometric abnormalities, we compared brain volumes from high-resolution T1 magnetic resonance images of 12 unmedicated subjects with BDD to images of 12 matched controls using voxel-based morphometry (VBM). In addition, we compared volumes in specific regions of interest including the IFG, amygdala, caudate, and total grey and white matter and examined correlations with symptom severity. VBM revealed no statistically significant volumetric differences, nor were there significant differences in any of the regions of interest. However, there were significant positive correlations between scores on the BDD version of the Yale-Brown Obsessive-Compulsive Disorder Scale (BDD-YBOCS) and volumes of the left IFG (r=0.69) and the right amygdala (r=0.54). These findings of correlations between BDD symptom severity and volumes of the left IFG and the right amygdala. These are in concordance with the involvement of these regions in pathological face processing, which may contribute to the primary symptomatology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.