Evidence map›Paper›PMID 19328650›Full record

Trial reportJournal of pain and symptom management2009

Acupressure bands are effective in reducing radiation therapy-related nausea.

Joseph A Roscoe, Peter Bushunow, Pascal Jean-Pierre, Charles E Heckler, Jason Q Purnell, Luke J Peppone, Yuhchyau Chen, Marilyn N Ling, Gary R Morrow

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of pain and symptom management, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A systematic review of methodologies, endpoints, and outcome measures in randomized trials of radiation therapy-induced nausea and vomiting.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Pooled it
  4. Pooled it
  5. Positive effects of acupressure bands combined with relaxation music/instructions on patients most at risk for chemotherapy-induced nausea.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
  6. Trial
  7. Article
  8. Complementary therapy use in metropolitan and regional Australian radiotherapy centres; do patients report effective outcomes?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  9. Antiemetic research: future directions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Joseph A RoscoeUniversity of Rochester James P Wilmot Cancer Center, Rochester, NY 14642, USA. joseph_roscoe@urmc.rochester.edu
Peter Bushunow
Pascal Jean-Pierre
Charles E Heckler
Jason Q Purnell
Luke J Peppone
Yuhchyau Chen
Marilyn N Ling
Gary R Morrow
University of Rochester · USRochester General Hospital · US

Funding

UNIVERSITY OF ROCHESTER--CCOP RESEARCH BASEU10CA037420 · NCI · UNIVERSITY OF ROCHESTER · PI MORROW, GARY R · 1985 to 2014
$21.1M
Cancer Control Research Training Curriculum (R25T)R25CA102618 · NCI · UNIVERSITY OF ROCHESTER · PI JANELSINS, MICHELLE C, MORROW, GARY R · 2004 to 2018
$6.7M
NCI NIH HHS 1R25-CA 102618-01A1NCI NIH HHS R25 CA102618NCI NIH HHS U10 CA037420
6 · The paper itself

Abstract

Previous studies have shown that acupressure bands can reduce chemotherapy-related nausea. Patients' expectations of efficacy account for part of this outcome. We conducted a three-arm randomized clinical trial to investigate the effectiveness of acupressure bands in controlling radiation therapy-induced nausea and to test whether an informational manipulation designed to increase expectation of efficacy would enhance the effectiveness of the acupressure bands. Patients who experienced nausea at prior treatments were randomized to either standard care (Arm 1, n=29) or standard care plus acupressure bands with either neutral (Arm 2, n=30) or positive (Arm 3, n=29) information regarding the efficacy of the bands. Patients reported nausea for two days prior to randomization (baseline) and for five days following using a seven-point semantic rating scale (1=not nauseated to 7=extremely nauseated). Patients in Arms 2 and 3 combined reported greater reduction in average nausea than patients in Arm 1 (P=0.01; mean(bands)=0.70, mean(no bands)=0.10). This equates to a 23.8% decrease in nausea in the band groups compared to a 4.8% decrease in the control group, a 19% difference. The informational manipulation failed to alter efficacy expectations and there was no statistically significant difference in nausea between patients in Arms 2 and 3. Acupressure bands are an effective, low-cost, nonintrusive, well-accepted, and safe adjunct to standard antiemetic medication. An attempt to boost the efficacy of the acupressure bands by providing positive information was not successful.

Indexed as

AcupressureAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNauseaNeoplasmsRadiotherapyVomitingYoung Adult

Identifiers

PMID19328650
PMCPMC2764274
OpenAlexW2010500148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.