Evidence map›Paper›PMID 19327589›Full record

ReviewHematology/oncology clinics of North America2009

Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention.

Grover C Bagby, Gabrielle Meyers

Abstract readReview
In one paragraph

Review in Hematology/oncology clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Grover C BagbyDepartment of Molecular and Medical Genetics, Oregon Health and Sciences University, Portland, OR, USA. grover@ohsu.edu
Gabrielle Meyers

Funding

Xenograft CoreP01HL048546 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI GROMPE, MARKUS · 1994 to 2020
$36.4M
YOUTH, Osteoporosis, and Understanding Total Health (YOUTH)M01RR000334 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI DORSA, DANIEL MICHAEL · 1985 to 2006
$30.6M
Fanconi Anemia stem cells allow molecular characterization of acute leukemiaR01CA138237 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI BAGBY, GROVER CARLTON, CLAPP, DAVID W · 2008 to 2012
$1.9M
Study of Clonal Dominance in Hematopoiesis in PNHK23RR020043 · NCRR · UNIVERSITY OF UTAH · PI MEYERS, GABRIELLE · 2004 to 2008
$674k
NCI NIH HHS R01 CA138237NCI NIH HHS R01 CA138237-01NCRR NIH HHS K23 RR 020043NCRR NIH HHS K23 RR020043NCRR NIH HHS M01 RR000334NHLBI NIH HHS 1P01 HL48546NHLBI NIH HHS P01 HL048546
6 · The paper itself

Abstract

Patients who have acquired and inherited bone marrow failure syndromes are at risk for the development of clonal neoplasms including acute myeloid leukemia, myelodysplastic syndrome, and paroxysmal nocturnal hemoglobinuria. This article reviews the evidence supporting a model of clonal selection, a paradigm that provides a reasonable expectation that these often fatal complications might be prevented in the future.

Indexed as

Acute DiseaseAnemia, AplasticAnimalsBone MarrowBone Marrow TransplantationCytokinesHumansLeukemiaMyelodysplastic SyndromesCytokines

Identifiers

PMID19327589
PMCPMC2697169

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.