ArticleVirology journal2009
Avian influenza virus (H5N1); effects of physico-chemical factors on its survival.
Article in Virology journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using the systematic review methodology to evaluate factors that influence the persistence of influenza virus in environmental matrices.Applied and environmental microbiology · 2011Pooled it
- Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells.PloS one · 2013Trial
- Comparative evaluation of different transport media for H5N1 highly pathogenic avian influenza virus.Scientific reports · 2025Article
- Rapid risk assessment to address emerging concerns of HPAI in raw and pasteurized milk.PloS one · 2025Article
- Article
- Article
- Mass mortality event in South American sea lions (The veterinary quarterly · 2023Article
- Modeling long-distance airborne transmission of highly pathogenic avian influenza carried by dust particles.Scientific reports · 2023Article
- The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-Zoonotic Avian Influenza andApplied biosafety : journal of the American Biological Safety Association · 2023Review
- Review
- Evaluation of Feedstuffs as a Potential Carrier of Avian Influenza Virus between Feed Mills and Poultry Farms.Pathogens (Basel, Switzerland) · 2022Article
- Surveillance of the spread of avian influenza virus type A in live bird markets in Tripoli, Libya, and determination of the associated risk factors.Veterinary world · 2022Article
- Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture.Autophagy · 2022Article
- Review of air disinfection approaches and proposal for thermal inactivation of airborne viruses as a life-style and an instrument to fight pandemics.Applied thermal engineering · 2022Review
- Sensitivity of influenza virus to ultraviolet irradiation.GMS hygiene and infection control · 2022Review
- Natural and Experimental Persistence of Highly Pathogenic H5 Influenza Viruses in Slurry of Domestic Ducks, with or without Lime Treatment.Applied and environmental microbiology · 2020Article
- Field-based method for assessing duration of infectivity for influenza A viruses in the environment.Journal of virological methods · 2020Article
- A virus precipitation method for concentration & detection of avian influenza viruses from environmental water resources & its possible application in outbreak investigations.The Indian journal of medical research · 2019Article
- Bactericidal and virucidal efficacies of food additive grade calcium hydroxide under various concentrations, organic material conditions, exposure duration, and its stability.Veterinary world · 2019Article
- Inhibitory effect of grapefruit seed extract (GSE) on avian pathogens.The Journal of veterinary medical science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Present study was performed to determine the effects of physical and chemical agents on infective potential of highly pathogenic avian influenza (HPAI) H5N1 (local strain) virus recently isolated in Pakistan during 2006 outbreak. H5N1 virus having titer 10(8.3) ELD(50)/ml was mixed with sterilized peptone water to get final dilution of 4HA units and then exposed to physical (temperature, pH and ultraviolet light) and chemical (formalin, phenol crystals, iodine crystals, CID 20, virkon-S, zeptin 10%, KEPCIDE 300, KEPCIDE 400, lifebuoy, surf excel and caustic soda) agents. Harvested amnio-allantoic fluid (AAF) from embryonated chicken eggs inoculated with H5N1 treated virus (0.2 ml/egg) was subjected to haemagglutination (HA) and haemagglutination inhibition (HI) tests. H5N1 virus lost infectivity after 30 min at 56 degrees C, after 1 day at 28 degrees C but remained viable for more than 100 days at 4 degrees C. Acidic pH (1, 3) and basic pH (11, 13) were virucidal after 6 h contact time; however virus retained infectivity at pH 5 (18 h), 7 and 9 (more than 24 h). UV light was proved ineffectual in inactivating virus completely even after 60 min. Soap (lifebuoy), detergent (surf excel) and alkali (caustic soda) destroyed infectivity after 5 min at 0.1, 0.2 and 0.3% dilution. All commercially available disinfectants inactivated virus at recommended concentrations. Results of present study would be helpful in implementing bio-security measures at farms/hatcheries levels in the wake of avian influenza virus (AIV) outbreak.
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