ArticleBMC genomics2009
A robust linkage map of the porcine autosomes based on gene-associated SNPs.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Genetic variation in recombination rate in the pig.Genetics, selection, evolution : GSE · 2021Article
- The genetic connectedness calculated from genomic information and its effect on the accuracy of genomic prediction.PloS one · 2018Article
- Article
- High-resolution genetic map for understanding the effect of genome-wide recombination rate on nucleotide diversity in watermelon.G3 (Bethesda, Md.) · 2014Article
- Meiotic recombination analyses of individual chromosomes in male domestic pigs (Sus scrofa domestica).PloS one · 2014Article
- A new genotype imputation method with tolerance to high missing rate and rare variants.PloS one · 2014Article
- Porcine dorfin: molecular cloning of the RNF19 gene, sequence comparison, mapping and expression analysis.Molecular biology reports · 2012Article
- A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content.BMC genomics · 2012Article
- The sex-specific impact of meiotic recombination on nucleotide composition.Genome biology and evolution · 2012Article
- A high-resolution linkage map for comparative genome analysis and QTL fine mapping in Asian seabass, Lates calcarifer.BMC genomics · 2011Article
- Assignment of chromosomal locations for unassigned SNPs/scaffolds based on pair-wise linkage disequilibrium estimates.BMC bioinformatics · 2010Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenetic linkage maps are necessary for mapping of mendelian traits and quantitative trait loci (QTLs). To identify the actual genes, which control these traits, a map based on gene-associated single nucleotide polymorphism (SNP) markers is highly valuable. In this study, the SNPs were genotyped in a large family material comprising more than 5,000 piglets derived from 12 Duroc boars crossed with 236 Danish Landrace/Danish Large White sows. The SNPs were identified in sequence alignments of 4,600 different amplicons obtained from the 12 boars and containing coding regions of genes derived from expressed sequence tags (ESTs) and genomic shotgun sequences.
resultsLinkage maps of all 18 porcine autosomes were constructed based on 456 gene-associated and six porcine EST-based SNPs. The total length of the averaged-sex whole porcine autosome was estimated to 1,711.8 cM resulting in an average SNP spacing of 3.94 cM. The female and male maps were estimated to 2,336.1 and 1,441.5 cM, respectively. The gene order was validated through comparisons to the cytogenetic and/or physical location of 203 genes, linkage to evenly spaced microsatellite markers as well as previously reported conserved synteny. A total of 330 previously unmapped genes and ESTs were mapped to the porcine autosome while ten genes were mapped to unexpected locations.
conclusionThe linkage map presented here shows high accuracy in gene order. The pedigree family network as well as the large amount of meiotic events provide good reliability and make this map suitable for QTL and association studies. In addition, the linkage to the RH-map of microsatellites makes it suitable for comparison to other QTL studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.