ReviewAnnual review of clinical psychology2009
When doors of perception close: bottom-up models of disrupted cognition in schizophrenia.
Review in Annual review of clinical psychology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 278 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
278 citing papers in PubMed, 2 syntheses or guidelines pooled it, 503 citations in OpenAlex.
- A Meta-analytic Review of Auditory Event-Related Potential Components as Endophenotypes for Schizophrenia: Perspectives From First-Degree Relatives.Schizophrenia bulletin · 2016Pooled it
- Neuroimaging distinction between neurological and psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2015Pooled it
- Visual remediation of contrast processing impairments in schizophrenia: A preliminary clinical trial.Schizophrenia research · 2024Trial
- Functional connectivity signatures of NMDAR dysfunction in schizophrenia-integrating findings from imaging genetics and pharmaco-fMRI.Translational psychiatry · 2023Trial
- Changes in emotion processing and social cognition with auditory versus visual neuroscience-informed cognitive training in individuals with schizophrenia.Schizophrenia research · 2022Trial
- Auditory versus visual neuroscience-informed cognitive training in schizophrenia: Effects on cognition, symptoms and quality of life.Schizophrenia research · 2020Trial
- Impact of baseline early auditory processing on response to cognitive remediation for schizophrenia.Schizophrenia research · 2019Trial
- Neurophysiologic measures of target engagement predict response to auditory-based cognitive training in treatment refractory schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Trial
- Computerized cognitive training is associated with improved psychosocial treatment engagement in schizophrenia.Schizophrenia research · 2018Trial
- Targeted cognitive training improves auditory and verbal outcomes among treatment refractory schizophrenia patients mandated to residential care.Schizophrenia research · 2018Trial
- The effect of bilateral transcranial direct current stimulation on early auditory processing in schizophrenia: a preliminary study.Journal of neural transmission (Vienna, Austria : 1996) · 2017Trial
- Nicotine restores functional connectivity of the ventral attention network in schizophrenia.Neuropharmacology · 2016Trial
- Trial
- Mismatch negativity matures in adolescence and without sensitivity to microglial depletion.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Protocol for analyzing slow cortical dynamics in mouse neuronal recordings.STAR protocols · 2026Article
- Emotion recognition misclassification patterns in individuals with psychotic spectrum disorders and history of interpersonal aggression.Schizophrenia (Heidelberg, Germany) · 2026Article
- Examining the diametric model of autistic and psychotic traits through temporal perception.Scientific reports · 2026Article
- Exploring the Pathways Between Early Auditory Processing, Processing Speed, Social Cognition, and Negative Symptoms on Social Functioning in Individuals at Clinical High Risk for Psychosis: A Structural Equation Modeling Approach.Biological psychiatry · 2026Article
- Visual suppression deficits as a biomarker of working memory impairment in schizophrenia.Schizophrenia research. Cognition · 2026Review
- Disturbed Functional Connectivity Between Anterior Default Mode and Sensory Processing Regions Is Linked to Peripheral Inflammatory Markers and Psychopathology in Schizophrenia.Schizophrenia bulletin · 2026Article
218 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Schizophrenia is a major mental disorder that affects approximately 1% of the population worldwide. Cognitive deficits are a key feature of schizophrenia and a primary cause of long-term disability. Current neurophysiological models of schizophrenia focus on distributed brain dysfunction with bottom-up as well as top-down components. Bottom-up deficits in cognitive processing are driven by impairments in basic perceptual processes that localize to primary sensory brain regions. Within the auditory system, deficits are apparent in elemental sensory processing, such as tone matching following brief delay. Such deficits lead to impairments in higher-order processes such as phonological processing and auditory emotion recognition. Within the visual system, deficits are apparent in functioning of the magnocellular visual pathway, leading to higher-order deficits in processes such as perceptual closure, object recognition, and reading. In both auditory and visual systems, patterns of deficit are consistent with underlying impairment of brain N-methyl-d-aspartate receptor systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.