Evidence map›Paper›PMID 19326508›Full record

ReviewCurrent opinion in allergy and clinical immunology2009

Asthma and ethnic minorities: socioeconomic status and beyond.

Erick Forno, Juan C Celedon

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Current opinion in allergy and clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 118 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00021840 completednot on this map

Genetic Epidemiology of Asthma in Costa Rica

TypeobservationalSponsorBrigham and Women's HospitalRan2001 to 2011Enrolled4,245ConditionsAsthma, Lung Diseases
NCT05292586 phase3completednot on this mapstarted 2022, after this paper: background citation

A 12 Week, Randomized, Double-blind, Multicenter, Active Controlled, 2-Arm Parallel Group Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose (Fixed Combination of Extrafine Beclomethasone Dipropionate Plus Formoterol Fumarate) Compared to CHF 718 pMDI 800µg Total Daily Dose (Extrafine Beclomethasone Dipropionate) in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid

TypeinterventionalSponsorChiesi Farmaceutici S.p.A.Ran2022 to 2024Enrolled1,377ConditionsAsthmaArmsBeclomethasone Dipropionate/Formoterol Fumarate, Beclomethasone Dipropionate
3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 3 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Is pesticide exposure a cause of obstructive airways disease?European respiratory review : an official journal of the European Respiratory Society · 2014
    Pooled it
  2. Cost-consequence analysis of multimodal interventions with environmental components for pediatric asthma in the state of Maryland.The Journal of asthma : official journal of the Association for the Care of Asthma · 2013
    Pooled it
  3. Pooled it
  4. Trial
  5. Income is an independent risk factor for worse asthma outcomes.The Journal of allergy and clinical immunology · 2018
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Bronchodilator response is linked with uncontrolled moderate-to-severe childhood asthma and elevated IL-4 and IL-13.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  12. Article
  13. Review
  14. Sequencing and health data resource of children of African ancestry.Genetics in medicine : official journal of the American College of Medical Genetics · 2026
    Article
  15. Article
  16. Real-World Adherence to Biologic Therapy for Severe Asthma in Children.The journal of allergy and clinical immunology. In practice · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Erick FornoDepartment of Pediatrics, Children's Hospital Boston, Massachusetts, USA.
Juan C Celedon
Harvard University · USMCPHS University · US

Funding

The Genetic Epidemiology of Asthma in Costa RicaR37HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2007 to 2015
$14.6M
SYSTEMS APPROACHES TO THE EPIDEMIOLOGY, GENETICS AND GENOMICS OF LUNG DISEASEST32HL007427 · NHLBI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI DAWN L DEMEO, Edwin K Silverman · 1985 to 2026
$13.6M
Molecular Basis of Pediatric DiseaseK12HD052892 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TERENCE S. DERMODY · 2007 to 2026
$6.5M
THE GENETIC EPIDEMIOLOGY OF ASTHMA IN COSTA RICAR01HL066289 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISS, SCOTT T · 2001 to 2005
$5.2M
Genes, Home Allergens and Asthma Puerto Rican ChildrenR01HL079966 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2006 to 2010
$3.8M
The Genetic Epidemiology of COPD in Costa RicaR01HL073373 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2005 to 2009
$3.5M
The Genetic Epidemiology of Asthma in Costa RicaK01HL004370 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CELEDON, JUAN CARLOS · 2001 to 2005
$697k
NHLBI NIH HHS HL04370NHLBI NIH HHS HL066289NHLBI NIH HHS HL073373NHLBI NIH HHS HL079966NHLBI NIH HHS K01 HL004370NHLBI NIH HHS R01 HL066289NHLBI NIH HHS R01 HL073373NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R37 HL066289NHLBI NIH HHS T32 HL007427NHLBI NIH HHS T32 HL07427
6 · The paper itself

Abstract

purpose of reviewWe aim to discuss current insights into our understanding of the mechanisms by which socioeconomic status influences the prevalence and severity of asthma in ethnic minorities. In addition, we review potential risk factors for ethnic disparities in asthma that are not mediated by socioeconomic status. RECENT

findingsExposures and factors correlated with ethnicity through socioeconomic status (e.g. indoor and outdoor air quality, smoke exposure, and access to healthcare) are likely to explain a significant proportion of the observed ethnic differences in asthma morbidity. However, other factors correlated with ethnicity (e.g. genetic variation) can impact ethnic disparities in asthma independently of and/or interacting with socioeconomic status-related factors. SUMMARY: Socioeconomic status is a rough marker of a variety of environmental/behavioral exposures and a very important determinant of differences in asthma prevalence and severity among ethnic minorities in the United States. However, socioeconomic status is unlikely to be the sole explanation for ethnic disparities in asthma, which may also be due to differences in genetic variation and gene-by-environment interactions among ethnic groups.

Indexed as

Racial GroupsSocioeconomic FactorsAsthmaDomestic ViolenceGenetic Predisposition to DiseaseHumansMinority GroupsPolymorphism, GeneticPovertyPrevalenceRisk FactorsStress, PsychologicalUnited States

Identifiers

PMID19326508
PMCPMC3920741
OpenAlexW2074791308

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.