ReviewCurrent opinion in allergy and clinical immunology2009
The role of indoor allergens in the development of asthma.
Review in Current opinion in allergy and clinical immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- SQ-standardized house dust mite immunotherapy as an immunomodulatory treatment in patients with asthma.Allergy · 2011Trial
- Impact of a household environmental intervention delivered by lay health workers on asthma symptom control in urban, disadvantaged children with asthma.American journal of public health · 2009Trial
- Risk Factors for COVID-19 mRNA Vaccine-Associated Exacerbations in Patients With Obstructive Airway Diseases: REsearch for Asthma and COPD ExacerbaTION Caused by COVID-19 mRNA Vaccination (REACTION Study).Allergy, asthma & immunology research · 2026Article
- EGFR inhibitors suppress house dust mite allergen Der pII induced inflammation in monocytes and macrophages.Frontiers in allergy · 2026Article
- Pets and related allergens modify the association between early life DEHP exposure and respiratory outcomes in children.Environmental research · 2025Article
- Microscopic Menaces: The Impact of Mites on Human Health.International journal of molecular sciences · 2024Review
- Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023Article
- Causal relationship betweenFrontiers in microbiology · 2023Article
- Treatment outcome clustering patterns correspond to discrete asthma phenotypes in children.Asthma research and practice · 2021Article
- Multigenerational Epigenetic Regulation of Allergic Diseases: Utilizing an Experimental Dust Mite-Induced Asthma Model.Frontiers in genetics · 2021Article
- Precision Medicine in Mite Allergic Rhinitis.Frontiers in allergy · 2021Review
- Effect of environmental exposures on allergen sensitization and the development of childhood allergic diseases: A large-scale population-based study.The World Allergy Organization journal · 2021Article
- Immune Modulation of Allergic Asthma by Early Pharmacological Inhibition of RIP2.ImmunoHorizons · 2020Article
- Sensitisation to airborne allergens as a risk factor for allergic rhinitis and asthma in the Polish population.Postepy dermatologii i alergologii · 2020Article
- Depiction of Major Mite Allergens in Severe Allergic Rhinitis with High Mite Perennial Exposure.Turkish archives of otorhinolaryngology · 2020Article
- Review
- Prevention of Allergic Asthma with Allergen Avoidance Measures and the Role of Exposome.Current allergy and asthma reports · 2020Review
- House dust mite-specific immunotherapy alters the natural course of atopic march.Journal of the Chinese Medical Association : JCMA · 2020Review
- The Effects of the Environment on Asthma Disease Activity.Immunology and allergy clinics of North America · 2019Review
- Indoor air quality in inner-city schools and its associations with building characteristics and environmental factors.Environmental research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
purpose of reviewAsthma prevalence has markedly increased over the past 30 years. Although atopy and exposure to environmental allergens are known to exacerbate asthma, recent literature supports a causal role of indoor allergens in disease development. RECENT
findingsHigh-risk birth cohorts continue to point to atopy as the main risk factor for developing asthma. Exposure to perennial allergens has also been linked to the development of asthma, though with less consistency. Intervention at the level of allergen exposure and allergic immune response is promising. SUMMARY: The current model of atopic asthma, the predominant phenotype, incorporates genetic and environmental factors in the development of disease. Although genetic factors are less malleable, the environmental component lends itself to analysis and modification.For many, the development of asthma starts with allergen exposure leading to atopic sensitization and subsequent disease. Several studies support the progression from exposure to sensitization with the potential of extremely high levels of exposure leading to tolerance. Likewise, the progression from atopy to asthma is well documented,especially in genetically predisposed children. Recent intervention trials confirm these findings and begin to show promise for the prevention of asthma by interrupting the allergen exposure==>allergen sensitization==>atopic asthma pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.