ArticlePediatric blood & cancer2009
Development of retinoblastoma programs in Central America.
Article in Pediatric blood & cancer, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Implementation factors of non-communicable disease policies and programmes for children and youth in low-income and middle-income countries: a systematic review.BMJ paediatrics open · 2024Pooled it
- Factors associated with level of knowledge on childhood cancer early warning signs among intern doctors in Tanzania.BMC medical education · 2026Article
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- Childhood Cancer Awareness Program in Bungoma County, Kenya.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Retinoblastoma management in China: clinical challenges.International journal of ophthalmology · 2025Review
- Retinoblastoma in a Young Nigerian Girl: A Case Report From ECWA Eye Hospital, Kano.Case reports in ophthalmological medicine · 2025Article
- Presentation pattern and survival rate of retinoblastoma following chemotherapy: a prospective study.BMC pediatrics · 2023Article
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- Epidemiological and Clinical Presentation of Retinoblastoma among Nepalese Children in 2019.South Asian journal of cancer · 2023Article
- Evaluation of a Health Care Worker Training Intervention to Improve the Early Diagnosis and Referral of Childhood Cancers in Ghana: A Qualitative Descriptive Study.JCO global oncology · 2022Article
- Improving Medical Students' Awareness About Retinoblastoma: A Practical Strategy.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Global Retinoblastoma Presentation and Analysis by National Income Level.JAMA oncology · 2020Article
- Challenge of Retinoblastoma in Mexico in 2020: Perspectives and Solutions.Journal of ophthalmology · 2020Review
- The Impact of Prospective Telemedicine Implementation in the Management of Childhood Acute Lymphoblastic Leukemia in Recife, Brazil.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2017Article
- Evaluation of continuing education of family health strategy teams for the early identification of suspected cases of cancer in children.BMC medical education · 2017Article
- Clinical, epidemiological, and therapeutic profile of patients with a retinoblastoma diagnosis experience in the Costa Rica National Children's Hospital Oncology Unit from January 2009 to December 2015.Ecancermedicalscience · 2017Article
- Retinoblastoma.Nature reviews. Disease primers · 2015Review
- Genotyping of Polymorphic Microsatellite Markers Linked to RB1 Locus in Iranian Population.Avicenna journal of medical biotechnology · 2012Article
- Preserving vision in retinoblastoma through early detection and intervention.Current oncology reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundRetinoblastoma, a curable eye tumor, is associated with poor survival in Central America (CA). To develop a retinoblastoma program in El Salvador, Guatemala, and Honduras, twinning initiatives were undertaken between local pediatric oncology centers, nonprofit foundations, St. Jude Children's Research Hospital, and the University of Tennessee Hamilton Eye Institute. PROCEDURE: The retinoblastoma program focused on developing early diagnosis programs in Honduras with national vaccination campaigns, developing treatment protocols suited to local conditions, building local networks of oncologists and ophthalmologists, training local healthcare providers, using modern donated equipment for diagnosis and treatment, and the ORBIS Cybersight consultation program and Internet meetings to further education and share expertise. Pediatric ophthalmologists and oncologists worked with foundations to treat patients locally with donated equipment and Internet consultations, or at the center in Guatemala.
resultsNumber of patients successfully treated increased after the program was introduced. For 2000-2003 and 2004-2007, patients abandoning/refusing treatment decreased in Guatemala from 20 of 95 (21%) to 14 of 123 (11%) and in Honduras from 13 of 37 (35%) to 7 of 37 (19%). Survival in El Salvador was good and abandonment/refusal low for both periods. Of 18 patients receiving focal therapy for advanced disease, 14 have single remaining eyes.
conclusionDevelopment of the program in CA has decreased abandonment/refusal and enabled ophthalmologists at local centers to use modern equipment to provide better treatment. This approach might serve as a guide for developing other multispecialty programs.
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Registered trials
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