Evidence map›Paper›PMID 19326395›Full record

ReviewJournal of cellular physiology2009

Applications of transgenics in studies of bone sialoprotein.

Jin Zhang, Qisheng Tu, Jake Chen

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cellular physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Expression of Non-collagenous Bone Matrix Proteins in Osteoblasts Stimulated by Mechanical Stretching in the Cranial Suture of Neonatal Mice.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2019
    Article
  6. Signaling of extracellular matrices for tissue regeneration and therapeutics.Tissue engineering and regenerative medicine · 2016
    Review
  7. Article
  8. Quantitative genetic study of the circulating osteopontin in community-selected families.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2011
    Article
  9. Dentin: structure, composition and mineralization.Frontiers in bioscience (Elite edition) · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jin ZhangDivision of Oral Biology, Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA.
Qisheng Tu
Jake Chen
Tufts University · US

Funding

Bone Marrow Stromal Cells in Oral and Craniofacial Tissue RegenerationR01DE016710 · NIDCR · TUFTS UNIVERSITY BOSTON · PI CHEN, JAKE JINKUN · 2007 to 2010
$1.4M
Cell Differentiation in Periodontal RegenerationR01DE014537 · NIDCR · TUFTS UNIVERSITY BOSTON · PI CHEN, JAKE JINKUN · 2003 to 2006
$1.3M
REGULATION OF BONE SIALOPROTEIN (BSP) EXPRESSION IN VIVOR29DE011088 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR SAN ANT · PI CHEN, JAKE JINKUN · 1995 to 1999
–
NIDCR NIH HHS DE14537NIDCR NIH HHS DE16710NIDCR NIH HHS R01 DE014537NIDCR NIH HHS R01 DE016710NIDCR NIH HHS R29 DE011088
6 · The paper itself

Abstract

Bone sialoprotein (BSP) is a major non-collagenous protein in mineralizing connective tissues such as dentin, cementum and calcified cartilage tissues. As a member of the Small Integrin-Binding Ligand, N-linked Glycoprotein (SIBLING) gene family of glycoproteins, BSP is involved in regulating hydroxyapatite crystal formation in bones and teeth, and has long been used as a marker gene for osteogenic differentiation. In the most recent decade, new discoveries in BSP gene expression and regulation, bone remodeling, bone metastasis, and bone tissue engineering have been achieved with the help of transgenic mice. In this review, we discuss these new discoveries obtained from the literatures and from our own laboratory, which were derived from the use of transgenic mouse mutants related to BSP gene or its promoter activity.

Indexed as

Mice, TransgenicAnimalsBone NeoplasmsBone RegenerationBone RemodelingCell DifferentiationGene Expression RegulationGene Expression Regulation, NeoplasticGenes, ReporterGenotypeIntegrin-Binding SialoproteinMiceOsteogenesisPhenotypePromoter Regions, GeneticSialoglycoproteinsIbsp protein, mouseIntegrin-Binding SialoproteinSialoglycoproteins

Identifiers

PMID19326395
PMCPMC2826241
OpenAlexW2133977020

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.