Evidence map›Paper›PMID 19326050›Full record

ReviewJournal of neuro-oncology2009

Primary anaplastic pleomorphic xanthoastrocytoma with widespread neuroaxis dissemination at diagnosis--a pediatric case report and review of the literature.

Toshiyuki Okazaki, Teruyoshi Kageji, Kazuhito Matsuzaki, Hidehisa Horiguchi, Takanori Hirose, Hiroyoshi Watanabe, Toshihiro Ohnishi, Shinji Nagahiro

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  5. The evolution of pleomorphic xanthoastrocytoma: from genesis to molecular alterations and mimics.Laboratory investigation; a journal of technical methods and pathology · 2022
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  14. Epithelioid GBMs show a high percentage of BRAF V600E mutation.The American journal of surgical pathology · 2013
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Toshiyuki OkazakiDepartment of Neurosurgery, School of Medicine, The University of Tokushima, Tokushima, Japan. tokazaki1978@sirius.ocn.ne.jp
Teruyoshi Kageji
Kazuhito Matsuzaki
Hidehisa Horiguchi
Takanori Hirose
Hiroyoshi Watanabe
Toshihiro Ohnishi
Shinji Nagahiro
Tokushima University · JPHyogo Prefectural Awaji Medical Center · JPSaitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 5 year-old boy with primary anaplastic pleomorphic xanthoastrocytoma (PXA) with whole neuroaxis dissemination at diagnosis who experienced the sudden onset of generalized convulsion. Head- and spinal magnetic resonance imaging (MRI) showed widespread gadolinium (Gd)-enhanced lesions extending to the bilateral frontal- and medial temporal lobes and the spinal cord. Subsequent MRI study demonstrated that the lesion size increased without any neurological deterioration. Under a histopathologic diagnosis of anaplastic PXA he underwent adjuvant chemotherapy consisting of 12 cycles of carboplatin and vincristine. The patient is alive without any neurological deficits; follow-up MRI showed that the lesions remained stable during 18 months of chemotherapy. We report a very rare pediatric case of primary anaplastic PXA with dissemination involving the entire neuroaxis at the time of diagnosis.

Indexed as

AstrocytomaBrain NeoplasmsChild, PreschoolDiagnosis, DifferentialHeadHumansMagnetic Resonance ImagingMaleNeoplasms, Complex and MixedSpinal CordTomography, X-Ray Computed

Identifiers

PMID19326050
OpenAlexW2012916943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.