ArticleMechanisms of development2009
Juvenile hormone regulation of male accessory gland activity in the red flour beetle, Tribolium castaneum.
Article in Mechanisms of development, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 91 citations in OpenAlex.
- Mechanisms Underlying Male Reproductive Toxicity Induced by Sublethal β-Cypermethrin Exposure inInsects · 2026Article
- Involvement of Taiman in juvenile hormone signaling controlling sexual maturation in a male moth.Current research in insect science · 2026Article
- Article
- Cloning and functional analysis of the juvenile hormone receptor gene CsMet in Coccinella septempunctata.Journal of insect science (Online) · 2024Article
- The impact of non-lethal doses of pyriproxyfen on male and femaleFrontiers in insect science · 2024Article
- Anatomical study of the red flour beetle using synchrotron radiation X-ray phase-contrast micro-tomography.Journal of anatomy · 2023Review
- Primary culture and endocrine functional analysis of Leydig cells in ducks (Frontiers in endocrinology · 2023Article
- Discovering novel reproductive genes in a non-model fly usingFrontiers in genetics · 2022Article
- Rapid Genomic Evolution Drives the Diversification of Male Reproductive Genes in Dung Beetles.Genome biology and evolution · 2021Article
- Metabolomics provide new insights into mechanisms of Wolbachia-induced paternal defects in Drosophila melanogaster.PLoS pathogens · 2021Article
- Crucial Role of Juvenile Hormone Receptor Components Methoprene-Tolerant and Taiman in Sexual Maturation of Adult Male Desert Locusts.Biomolecules · 2021Article
- Transcriptome Analysis ofFrontiers in physiology · 2020Article
- Article
- Epigenetic modifications acetylation and deacetylation play important roles in juvenile hormone action.BMC genomics · 2018Article
- JH biosynthesis and hemolymph titers in adult male Aedes aegypti mosquitoes.Insect biochemistry and molecular biology · 2018Article
- A plant diterpene counteracts juvenile hormone-mediated gene regulation during Drosophila melanogaster larval development.PloS one · 2018Article
- Multiple functions of CREB-binding protein during postembryonic development: identification of target genes.BMC genomics · 2017Article
- Effects of juvenile hormone analogue (methoprene) and 20-hydroxyecdysone on reproduction in Polygonia c-aureum (Lepidoptera: Nymphalidae) in relation to adult diapause.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Article
- Toxicity of Naphthalene and Benzene on Tribollium castaneum Herbst.International journal of environmental research and public health · 2017Article
- Endocrine network essential for reproductive success inProceedings of the National Academy of Sciences of the United States of America · 2017Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Male accessory gland proteins (Acps) act as key modulators of reproductive success in insects by influencing the female reproductive physiology and behavior. We used custom microarrays and identified 112 genes that were highly expressed in male accessory glands (MAG) in the red flour beetle, Tribolium castaneum. Out of these 112 identified genes, 59 of them contained sequences coding for signal peptide and cleavage site and the remaining 53 contained transmembrane domains. The expression of 14 of these genes in the MAG but not in other tissues of male or female was confirmed by quantitative real-time PCR. In virgin males, juvenile hormone (JH) levels increased from second day post adult emergence (PAE), remained high on third day PAE and declined on fourth day PAE. The ecdysteroid titers were high soon after adult emergence but declined to minimal levels from 1 to 5 days PAE. Feeding of juvenile hormone analog, hydroprene, but not the ecdysteroid analog, RH-2485, showed an increase in size of MAGs, as well as an increase in total RNA and protein content of MAG. Hydroprene treatment also increased the expression of Acp genes in the MAG. RNAi-mediated knock-down in the expression of JHAMT gene decreased the size of MAGs and expression of Acps. JH deficiency influenced male reproductive fitness as evidenced by a less vigor in mating behavior, poor sperm transfer, low egg and the progeny production by females mated with the JH deficient males. These data suggest a critical role for JH in the regulation of male reproduction especially through MAG secretions.
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