ArticleNeuron2009
Subcellular topography of visually driven dendritic activity in the vertebrate visual system.
Article in Neuron, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Canalization of circuit assembly by δ-protocadherins in the zebrafish optic tectum.bioRxiv : the preprint server for biology · 2025Article
- Morphology and synapse topography optimize linear encoding of synapse numbers inbioRxiv : the preprint server for biology · 2024Article
- DSCAM is differentially patterned along the optic axon pathway in the developing Xenopus visual system and guides axon termination at the target.Neural development · 2022Article
- Emergence of synaptic organization and computation in dendrites.Neuroforum · 2022Review
- Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons.Nature communications · 2020Article
- Hypothalamic Projections to the Optic Tectum in Larval Zebrafish.Frontiers in neuroanatomy · 2017Article
- Article
- Fine and distributed subcellular retinotopy of excitatory inputs to the dendritic tree of a collision-detecting neuron.Journal of neurophysiology · 2016Article
- Emergence of Selectivity to Looming Stimuli in a Spiking Network Model of the Optic Tectum.Frontiers in neural circuits · 2016Article
- Dendritic nonlinearities are tuned for efficient spike-based computations in cortical circuits.eLife · 2015Article
- Qualitatively different effect of repeated stress during adolescence on principal neuron morphology across lateral and basal nuclei of the rat amygdala.Neuroscience · 2015Article
- General features of the retinal connectome determine the computation of motion anticipation.eLife · 2015Article
- Article
- The horizontal brain slice preparation: a novel approach for visualizing and recording from all layers of the tadpole tectum.Journal of neurophysiology · 2015Article
- Subcellular mapping of dendritic activity in optic flow processing neurons.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2014Article
- An Augmented Two-Layer Model Captures Nonlinear Analog Spatial Integration Effects in Pyramidal Neuron Dendrites.Proceedings of the IEEE. Institute of Electrical and Electronics Engineers · 2014Article
- Monitoring synaptic and neuronal activity in 3D with synthetic and genetic indicators using a compact acousto-optic lens two-photon microscope.Journal of neuroscience methods · 2014Article
- Mechanisms underlying subunit independence in pyramidal neuron dendrites.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- A synaptic mechanism for network synchrony.Frontiers in cellular neuroscience · 2014Review
- Modeling human neurodevelopmental disorders in the Xenopus tadpole: from mechanisms to therapeutic targets.Disease models & mechanisms · 2013Review
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2 authors.
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Abstract
Neural pathways projecting from sensory organs to higher brain centers form topographic maps in which neighbor relationships are preserved from a sending to a receiving neural population. Sensory input can generate compartmentalized electrical and biochemical activity in the dendrites of a receiving neuron. Here, we show that in the developing retinotectal projection of young Xenopus tadpoles, visually driven Ca2+ signals are topographically organized at the subcellular, dendritic scale. Functional in vivo two-photon Ca2+ imaging revealed that the sensitivity of dendritic Ca2+ signals to stimulus location in visual space is correlated with their anatomical position within the dendritic tree of individual neurons. This topographic distribution was dependent on NMDAR activation, whereas global Ca2+ signals were mediated by Ca2+ influx through dendritic, voltage-dependent Ca2+ channels. These findings suggest a framework for plasticity models that invoke local dendritic Ca2+ signaling in the elaboration of neural connectivity and dendrite-specific information storage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.