ArticleThe journal of physical chemistry. B2009
Crowding effects of membrane proteins.
Article in The journal of physical chemistry. B, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Biomolecular assemblies through weak noncovalent interactions: Higher-order transient structures and their condensate phase.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Anthraquinones Inhibit Insulin Amyloidosis in Crowded Environments.Molecules (Basel, Switzerland) · 2026Article
- The configurational length scale in the self-assembly and modulation of higher-order transient protein structures.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Membrane Association of Intrinsically Disordered Proteins.Annual review of biophysics · 2025Review
- Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors.Computers in biology and medicine · 2022Article
- Pattern formation and polarity sorting of driven actin filaments on lipid membranes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Clustering and dynamics of crowded proteins near membranes and their influence on membrane bending.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Influenza A M2 Channel Clustering at High Protein/Lipid Ratios: Viral Budding Implications.Biophysical journal · 2019Article
- Equilibrium Modeling of the Mechanics and Structure of the Cancer Glycocalyx.Biophysical journal · 2019Article
- Crowding in Cellular Environments at an Atomistic Level from Computer Simulations.The journal of physical chemistry. B · 2017Article
- Membrane Shape Instability Induced by Protein Crowding.Biophysical journal · 2016Article
- Intramembrane congestion effects on lysenin channel voltage-induced gating.European biophysics journal : EBJ · 2016Article
- Single Molecule Imaging Deciphers the Relation between Mobility and Signaling of a Prototypical G Protein-coupled Receptor in Living Cells.The Journal of biological chemistry · 2015Article
- Mechanical transduction by ion channels: A cautionary tale.World journal of neurology · 2015Article
- EmrE dimerization depends on membrane environment.Biochimica et biophysica acta · 2014Article
- Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery.Drug discovery today · 2014Review
- Helical membrane protein conformations and their environment.European biophysics journal : EBJ · 2013Review
- Stochastic transitions in a bistable reaction system on the membrane.Journal of the Royal Society, Interface · 2013Article
- Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?BMC biophysics · 2013Article
- Reduced lateral mobility of lipids and proteins in crowded membranes.PLoS computational biology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In cell membranes, membrane proteins occupy approximately 30% of the total surface area. Crowding effects similar to those in the solution phase are thus to be expected. In addition, there are crowding effects unique to proteins bound to the two-dimensional membranes, such as those exerted on the equilibration of a protein between two membrane orientations and on the redistribution of proteins between different locations in a cell membrane. This article aims to present a theoretical framework for understanding the various crowding effects within membranes. For illustration, the theory is used to analyze previously published experimental and simulation data. It is hoped that the article will encourage quantitative analyses in future experiments and spur systematic investigation of membrane crowding effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.