ArticleNature neuroscience2009
The quest for action potentials in C. elegans neurons hits a plateau.
Article in Nature neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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Who cites it
41 citing papers in PubMed.
- A data-driven biology-based network model reproduces C. elegans premotor neural dynamics.PLoS computational biology · 2025Article
- Voltage-gated ion channel diversity underlies neuronal excitability and nervous system evolution.Nature communications · 2025Article
- An unusual potassium conductance protectsProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ultrastructural Analysis Reveals Mitochondrial Placement Independent of Synapse Placement in Fine Caliber C. elegans Neurons.The Journal of comparative neurology · 2024Article
- Article
- See Elegans: Simple-to-use, accurate, and automatic 3D detection of neural activity from densely packed neurons.PloS one · 2024Article
- A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress.iScience · 2023Article
- The synaptic organization in theProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Multisensory Integration inBrain sciences · 2022Review
- Fixed Point Attractor Theory Bridges Structure and Function inFrontiers in neuroscience · 2022Article
- Article
- Chemosensory signal transduction in Caenorhabditis elegans.Genetics · 2021Review
- Structural aspects of the aging invertebrate brain.Cell and tissue research · 2021Review
- Computing Temporal Sequences Associated With Dynamic Patterns on theFrontiers in systems neuroscience · 2021Article
- Minimum number of synaptic vesicles for the initiation of a single action potential atmicroPublication biology · 2020Article
- Collapse of Global Neuronal States in Caenorhabditis elegans under Isoflurane Anesthesia.Anesthesiology · 2020Article
- Biophysical modeling of C. elegans neurons: Single ion currents and whole-cell dynamics of AWCon and RMD.PloS one · 2019Article
- Breakdown of Neural Function under Isoflurane Anesthesia: In Vivo, Multineuronal Imaging in Caenorhabditis elegans.Anesthesiology · 2018Article
- From head to tail: a neuromechanical model of forward locomotion inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Nociceptive Biology of Molluscs and Arthropods: Evolutionary Clues About Functions and Mechanisms Potentially Related to Pain.Frontiers in physiology · 2018Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The small size and high resistance of C. elegans neurons makes them sensitive to the random opening of single ion channels, probably rendering codes that are based on classical, all-or-none action potentials unworkable. The recent discovery in C. elegans of a special class of regenerative events known as plateau potentials introduces the possibility of digital neural codes. Such codes would solve the problem of representing information in nervous systems in which action potentials are unreliable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.