Evidence map›Paper›PMID 19321564›Full record

ArticleThe American journal of clinical nutrition2009

Association between n-3 fatty acid consumption and ventricular ectopy after myocardial infarction.

Patrick J Smith, James A Blumenthal, Michael A Babyak, Anastasia Georgiades, Andrew Sherwood, Michael H Sketch, Lana L Watkins

Open access · greenAbstract read
In one paragraph

Article in The American journal of clinical nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Patrick J SmithDepartments of Psychiatry and Behavioral Sciences and Medicine, Duke University, Durham, NC, USA.
James A Blumenthal
Michael A Babyak
Anastasia Georgiades
Andrew Sherwood
Michael H Sketch
Lana L Watkins
Duke University · US

Funding

Exercise, Depression, and Cardiac RiskR01HL080664 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A · 2006 to 2010
$3.7M
Depression and Autonomic Control in Post-MI PatientsR01HL070954 · NHLBI · DUKE UNIVERSITY · PI WATKINS, LANA L · 2003 to 2006
$2.0M
ANXIETY &VAGAL CONTROL OF THE HEART IN CORONARY DISEASER01HL060826 · NHLBI · DUKE UNIVERSITY · PI WATKINS, LANA L · 1999 to 2002
$581k
NHLBI NIH HHS HL060826NHLBI NIH HHS HL070954NHLBI NIH HHS HL080664-01A1
6 · The paper itself

Abstract

backgroundn-3 (omega-3) Fatty acids are associated with a reduced risk of cardiovascular disease; however, the relation between dietary intake of n-3 fatty acids and ventricular arrhythmias has not been investigated among acute post-myocardial infarction (AMI) patients-a group at elevated risk of malignant arrhythmias.

objectiveThe objective was to examine the association between n-3 fatty acid consumption and ventricular ectopy among AMI patients.

designIn 260 AMI patients, dietary intake of n-3 fatty acids was assessed by using the Harvard food-frequency questionnaire, and ventricular ectopy was estimated from 24-h electrocardiograph recordings.

resultsA greater intake of n-3 fatty acids (eicosapentaenoic acid + docosahexaenoic acid + docosapentaenoic acid + alpha-linolenic acid) was associated with lower ventricular ectopy (beta = -0.35, P = 0.011), and this effect remained after cardiovascular comorbidities were controlled for (beta = -0.47, P = 0.003). Higher concentrations of both marine-based (eicosapentaenoic acid + docosahexaenoic acid) (beta = -0.21, P = 0.060) and plant-based (alpha-linolenic acid) (beta = -0.33, P = 0.024) fatty acids remained associated with lower ventricular ectopy after cardiovascular comorbidities were controlled for.

conclusionThese findings extend existing evidence linking n-3 fatty acid consumption to a reduced risk of ventricular arrhythmias by showing that a greater intake of n-3 fatty acids may be associated with low ventricular ectopy among AMI patients.

Indexed as

Dietary FatsAdultArrhythmias, CardiacBody Mass IndexCardiovascular DiseasesCoronary Artery BypassCoronary StenosisElectrocardiographyFatty Acids, Omega-3Feeding BehaviorHeart RateHumansMiddle AgedMyocardial InfarctionReproducibility of ResultsRisk FactorsDietary FatsFatty Acids, Omega-3

Identifiers

PMID19321564
PMCPMC2676996
OpenAlexW2113071011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.