ArticleExperimental dermatology2009
Frontiers and controversies in the pathobiology of vitiligo: separating the wheat from the chaff.
Article in Experimental dermatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 61 citations in OpenAlex.
- A Rare Case of Congenital Vitiligo in a Neonate.The Journal of clinical and aesthetic dermatology · 2021Article
- Effects of a Traditional Caraway Formulation on Experimental Models of Vitiligo and Mechanisms of Melanogenesis.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Clinical and Molecular Aspects of Vitiligo Treatments.International journal of molecular sciences · 2018Review
- Prevalence and Clinical Characteristics of Itch in Vitiligo and Its Clinical Significance.BioMed research international · 2017Article
- AHR promoter variant modulates its transcription and downstream effectors by allele-specific AHR-SP1 interaction functioning as a genetic marker for vitiligo.Scientific reports · 2015Article
- Highlights in pathogenesis of vitiligo.World journal of clinical cases · 2015Review
- Polymorphisms in Toll-like receptor genes are associated with vitiligo.Frontiers in genetics · 2015Article
- Current aspects of vitiligo genetics.Postepy dermatologii i alergologii · 2014Review
- Colocalization of vitiligo and alopecia areata: coincidence or consequence?International journal of trichology · 2013Article
- Six decades of vitiligo genetics: genome-wide studies provide insights into autoimmune pathogenesis.The Journal of investigative dermatology · 2012Review
- Transcriptome analysis reveals markers of aberrantly activated innate immunity in vitiligo lesional and non-lesional skin.PloS one · 2012Article
- The Newest Hypothesis about Vitiligo: Most of the Suggested Pathogeneses of Vitiligo Can Be Attributed to Lack of One Factor, Zinc-α2-Glycoprotein.ISRN dermatology · 2012Article
- Association study between polymorphisms of CD28, CTLA4 and ICOS and non-segmental vitiligo in a Korean population.Experimental and therapeutic medicine · 2011Article
- Recent progress in the genetics of generalized vitiligo.Journal of genetics and genomics = Yi chuan xue bao · 2011Review
- Shared genetic relationships underlying generalized vitiligo and autoimmune thyroid disease.Thyroid : official journal of the American Thyroid Association · 2010Review
- Clinical characteristics and PTPN22 1858C/T variant analysis in Jordanian Arab vitiligo patients.Molecular diagnosis & therapy · 2010Article
- Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.The Journal of investigative dermatology · 2010Article
- Biochemical aspects of mammalian melanocytes and the emerging role of melanocyte stem cells in dermatological therapies.International journal of health sciencesReview
- Hypothesis: zinc can be effective in treatment of vitiligo.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The pathogenesis of vitiligo is complex and not well understood. Genes play a role in all aspects of vitiligo pathogenesis, and studies are ongoing to identify these genes and understand their biology. There is a body of interlocking, compelling evidence supporting an autoimmune basis for most or all cases of generalized vitiligo. The development of an autoimmune disease generally involves three components; the immune system, environmental triggers and other exogenous precipitating factors, and the target tissue. In vitiligo, precipitating factors could induce melanocyte damage in genetically susceptible individuals and consequent cell death, loss of tolerance, and induction of melanocyte-directed autoimmunity. Future research will more precisely define the multiple biological events that regulate development of vitiligo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.