ArticleThe Pediatric infectious disease journal2009
Pyuria associated with acute Kawasaki disease and fever from other causes.
Article in The Pediatric infectious disease journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 45 citations in OpenAlex.
- Use of Machine Learning to Differentiate Children With Kawasaki Disease From Other Febrile Children in a Pediatric Emergency Department.JAMA network open · 2023Article
- Sterile Pyuria in Kawasaki Disease: A Large Prospective Cohort Study.Frontiers in cardiovascular medicine · 2022Article
- Cerebrospinal fluid changes and clinical features of aseptic meningitis in patients with Kawasaki disease.The Journal of international medical research · 2021Article
- 2021 Update on the Clinical Management and Diagnosis of Kawasaki Disease.Current infectious disease reports · 2021Review
- The Differential Diagnosis of Sterile Pyuria in Pediatric Patients: A Review.Global pediatric health · 2021Review
- Kawasaki Disease: an Update.Current rheumatology reports · 2020Review
- Prevalence and characteristics of arthritis in Kawasaki disease: a Chinese cohort study.Clinical and experimental medicine · 2019Article
- Differentiating Kawasaki disease from urinary tract infection in febrile children with pyuria and C-reactive protein elevation.Italian journal of pediatrics · 2018Article
- Pyuria in patients with Kawasaki disease.World journal of clinical pediatrics · 2015Review
- High dose Anakinra for treatment of severe neonatal Kawasaki disease: a case report.Pediatric rheumatology online journal · 2014Article
- Kidney and urinary tract involvement in kawasaki disease.International journal of pediatrics · 2013Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Despite the widespread recognition of pyuria in acute Kawasaki disease (KD) patients and its inclusion in the American Heart Association list of supporting laboratory data for KD diagnosis, no systematic study of pyuria and the origin of these cells in KD patients have been reported. We used automated urinalysis with flow cytometry to characterize urine samples from 135 acute KD subjects and 87 febrile control (FC) subjects without urinary tract infection. Pyuria [defined as > or =12 (for males) or 20 (for females) cells/microL] was present in 79.8% of KD and 54.0% of FC subjects (P < 0.0001). The median number of white blood cells (WBC) in the urine was 42 WBC/microL in KD and 12 WBC/microL in FC (P < 0.0001). No significant difference between the groups was seen for urine red blood cell (RBC) count, protein, or specific gravity. Comparison of voided versus catheter-collected urine samples indicated an origin of the cells from the bladder or upper urinary tract in both patient groups. Pyuria in KD subjects was not correlated with age or day of illness. Overall, the presence of pyuria was neither specific nor sensitive as a marker for KD, but the magnitude of pyuria was significantly higher in KD patients compared with the FC group.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.