ArticleBMC neuroscience2009
Sexual differentiation of the zebra finch song system: potential roles for sex chromosome genes.
Article in BMC neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 61 citations in OpenAlex.
- Early testosterone exposure during development advances myelination and affects neurogenesis of the vocal control motor path in male zebra finches (Taeniopygia guttata).Journal of neuroendocrinology · 2025Article
- Article
- Dynamic transcriptome landscape in the song nucleus HVC between juvenile and adult zebra finches.Advanced genetics (Hoboken, N.J.) · 2021Article
- Estrogen and sex-dependent loss of the vocal learning system in female zebra finches.Hormones and behavior · 2021Article
- DNA Methylation Regulates Transcription Factor-Specific Neurodevelopmental but Not Sexually Dimorphic Gene Expression Dynamics in Zebra Finch Telencephalon.Frontiers in cell and developmental biology · 2021Article
- Estrogen Formation and Inactivation Following TBI: What we Know and Where we Could go.Frontiers in endocrinology · 2020Review
- Neural activity associated with rhythmicity of song in juvenile male and female zebra finches.Behavioural processes · 2019Article
- Inhibition of TrkB limits development of the zebra finch song system.Brain research · 2016Article
- It takes a seasoned bird to be a good listener: communication between the sexes.Current opinion in neurobiology · 2016Review
- Genetic regulation of sex differences in songbirds and lizards.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Dynamic gene expression in the song system of zebra finches during the song learning period.Developmental neurobiology · 2015Article
- Masculinisation of the zebra finch song system: roles of oestradiol and the Z-chromosome gene tubulin-specific chaperone protein A.Journal of neuroendocrinology · 2015Article
- Dynamic variation in forebrain estradiol levels during song learning.Developmental neurobiology · 2015Article
- Evaluation of reference genes for quantitative real-time PCR in the brain, pituitary, and gonads of songbirds.Hormones and behavior · 2014Article
- Quantitative integration of genetic factors in the learning and production of canary song.Proceedings. Biological sciences · 2014Article
- Article
- Sexually dimorphic and developmentally regulated expression of tubulin-specific chaperone protein A in the LMAN of zebra finches.Neuroscience · 2013Article
- Peripheral androgen receptors sustain the acrobatics and fine motor skill of elaborate male courtship.Endocrinology · 2013Article
- Structure and function of biotin-dependent carboxylases.Cellular and molecular life sciences : CMLS · 2013Review
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRecent evidence suggests that some sex differences in brain and behavior might result from direct genetic effects, and not solely the result of the organizational effects of steroid hormones. The present study examined the potential role for sex-biased gene expression during development of sexually dimorphic singing behavior and associated song nuclei in juvenile zebra finches.
resultsA microarray screen revealed more than 2400 putative genes (with a false discovery rate less than 0.05) exhibiting sex differences in the telencephalon of developing zebra finches. Increased expression in males was confirmed in 12 of 20 by qPCR using cDNA from the whole telencephalon; all of these appeared to be located on the Z sex chromosome. Six of the genes also showed increased expression in one or more of the song control nuclei of males at post-hatching day 25. Although the function of half of the genes is presently unknown, we have identified three as: 17-beta-hydroxysteroid dehydrogenase type IV, methylcrotonyl-CoA carboxylase, and sorting nexin 2.
conclusionThe data suggest potential influences of these genes in song learning and/or masculinization of song system morphology, both of which are occurring at this developmental stage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.