Evidence map›Paper›PMID 19309167›Full record

ArticleACS nano2009

Micro-mirrors for nanoscale three-dimensional microscopy.

Kevin Seale, Chris Janetopoulos, John Wikswo

Abstract readComment
In one paragraph

Article in ACS nano, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. A microfluidic-enabled mechanical microcompressor for the immobilization of live single- and multi-cellular specimens.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada · 2014
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Kevin SealeDepartment of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235-1807, USA.
Chris Janetopoulos
John Wikswo

Funding

PI(3,4,5)P3 Regulates Cell Polarity During Chemotaxis and CytokinesisR01GM080370 · NIGMS · VANDERBILT UNIVERSITY · PI JANETOPOULOS, CHRISTOPHER J · 2008 to 2012
$1.4M
NIGMS NIH HHS R01 GM080370
6 · The paper itself

Abstract

A research-grade optical microscope is capable of resolving fine structures in two-dimensional images. However, three-dimensional resolution, or the ability of the microscope to distinguish between objects lying above or below the focal plane from in-focus objects, is not nearly as good as in-plane resolution. In this issue of ACS Nano, McMahon et al. report the use of mirrored pyramidal wells with a conventional microscope for rapid, 3D localization and tracking of nanoparticles. Mirrors have been used in microscopy before, but recent work with MPWs is unique because it enables the rapid determination of the x-, y-, and z-position of freely diffusing nanoparticles and cellular nanostructures with unprecedented speed and spatial accuracy. As inexpensive tools for 3D visualization, mirrored pyramidal wells may prove to be invaluable aids in nanotechnology and engineering of nanomaterials.

Indexed as

HelianthusImaging, Three-DimensionalMicroscopyOptics and PhotonicsPollenSaccharomyces cerevisiae

Identifiers

PMID19309167
PMCPMC3839291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.