SynthesisMedical oncology (Northwood, London, England)2010
Treatment of low-grade gastric MALT-lymphoma unresponsive to Helicobacter pylori therapy: a pooled-data analysis.
Synthesis in Medical oncology (Northwood, London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 48 citations in OpenAlex.
- Gastric MALT Lymphoma in Plummer-Vinson Syndrome: Broadening the Spectrum of Associated Malignancies.ACG case reports journal · 2026Article
- Clinical management of gastric mucosa-associated lymphoid tissue lymphoma.The Korean journal of internal medicine · 2026Review
- Diagnosis and Treatment for Gastric Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma.Journal of clinical medicine · 2022Review
- Radiotherapy for localized gastric mucosa-associated lymphoid tissue lymphoma: long-term outcomes over 10 years.Journal of radiation research · 2017Article
- Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphomas: A review.World journal of gastroenterology · 2015Review
- Gastric MALT lymphoma: old and new insights.Annals of gastroenterology · 2014Review
- Clinical outcomes of radiation therapy for early-stage gastric mucosa-associated lymphoid tissue lymphoma.World journal of gastroenterology · 2013Article
- Treatment of gastric MALT lymphoma with a focus on Helicobacter pylori eradication.International journal of hematology · 2013Review
- Comparative outcomes of oncologic therapy in gastric extranodal marginal zone (MALT) lymphoma: analysis of the SEER-Medicare database.Annals of oncology : official journal of the European Society for Medical Oncology · 2013Article
- Pathogenetic mechanisms of hepatitis C virus-induced B-cell lymphomagenesis.Clinical & developmental immunology · 2012Review
- Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma.World journal of gastroenterology · 2010Article
- Gastric low-grade mucosal-associated lymphoid tissue-lymphoma: Helicobacter pylori and beyond.World journal of gastrointestinal oncology · 2010Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most favourable therapeutic strategy for gastric MALT-lymphoma not responding to Helicobacter pylori eradication still remains unclear, neither official guidelines nor randomised studies being available. We therefore performed a systematic review of the literature to evaluate the efficacy of different therapeutic approaches in these patients. Data regarding 315 patients were valuable, and lymphoma remission following the first therapeutic attempt was achieved in 90.1% cases. The most used therapy was radiotherapy (112 patients), followed by surgery (80 patients) and chemotherapy (68 patients), whilst a combination therapy was less frequent. Radiotherapy achieved a higher remission rate as compared to chemotherapy (97.3 vs. 85.3%; P = 0.007), being similar to surgery (97.3 vs. 92.5%; P = 0.2). No difference emerged when comparing lymphoma remission rate achieved by a single therapy with that of combined treatments (89.6 vs. 96.4%; P = 0.6). This is the first pooled-data analysis assessing the efficacy of different oncologic therapeutic approaches to treat gastric MALT-lymphoma unresponsive to H. pylori eradication. Radiotherapy seems to be the most suitable treatment in these patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.