ArticleJournal of children's orthopaedics2008
Skeletal features of primary hyperoxaluria type 1, revisited.
Article in Journal of children's orthopaedics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Natural History of Advanced Primary Hyperoxaluria Type 1: A Retrospective Study.Kidney medicine · 2025Article
- Hyperoxaluria: Diagnosis and Treatment.The Urologic clinics of North America · 2025Review
- Diagnosis and management of primary hyperoxalurias: best practices.Pediatric nephrology (Berlin, Germany) · 2024Review
- Late Presentation of Primary Oxalosis, Microcrystalline Arthropathy, and Tumoral Calcinosis: A Case Report and a Literature Review.Current rheumatology reviews · 2024Review
- Bone health in children with primary hyperoxaluria type 1 following liver and kidney transplantation.Frontiers in pediatrics · 2024Article
- Efficacy and safety of lumasiran for infants and young children with primary hyperoxaluria type 1: 30-month analysis of the phase 3 ILLUMINATE-B trial.Frontiers in pediatrics · 2024Article
- Three Tesla magnetic resonance imaging detects oxalate osteopathy in patients with primary hyperoxaluria type I.Pediatric nephrology (Berlin, Germany) · 2023Article
- Primary hyperoxaluria: spectrum of clinical and imaging findings.Pediatric radiology · 2017Review
- Primary hyperoxaluria detected by bone marrow biopsy: case report.BMC clinical pathology · 2017Article
- Bone impairment in primary hyperoxaluria: a review.Pediatric nephrology (Berlin, Germany) · 2016Review
- [Late diagnosis of a primary hyperoxaluria in terminal stage of chronic renal failure with severe hypoparathyroidism].The Pan African medical journal · 2014Article
- Treatment of nongout joint deposition diseases: an update.Arthritis · 2014Review
- Update on oxalate crystal disease.Current rheumatology reports · 2013Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to describe the skeletal manifestations of primary hyperoxaluria type 1 (PH1), the most common of the primary hyperoxalurias.
methodsWe clinically and radiographically reviewed 12 consecutive patients diagnosed with PH1, aged between 2 and 17 years. All patients had evidence of some type of renal involvement, 4 of whom were at end-stage renal disease (ESRD) and were under dialysis.
resultsThe main symptom was skeletal pain and was present only in the 4 severely involved patients and appeared during the second year of dialysis. The 2 most severely involved patients had evidence of pathological fractures. Radiological signs were present in patients with or without symptoms. These radiological signs were of two distinct types: those almost specific of oxalosis, such as dense and radiolucent metaphyseal bands and vertebral osteocondensations, which are found mainly in the severely involved individuals, and those less specific, such as signs of renal osteodystrophy, which are also found in less severely involved patients. Interestingly, our study revealed the presence of spondylolysis in 25% of cases. This latter finding is unique and has not previously been reported in the literature.
conclusionsThe skeletal manifestations of PH1 include specific and less specific radiological signs, with some patients being asymptomatic, and others presenting with bone pain and pathological fractures, as well as spondylolysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.