Evidence map›Paper›PMID 19308265›Full record

ArticleJournal of clinical biochemistry and nutrition2009

Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication.

Toshihiro Nishizawa, Hidekazu Suzuki, Toshifumi Hibi

Abstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. BioMed research international · 2017
    Trial
  2. Trial
  3. Article
  4. Levofloxacin and Rifampin Resistance inAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Development and validation of next-generation sequencing panel for personalizedFrontiers in cellular and infection microbiology · 2024
    Article
  6. Newer, Older, and Alternative Agents for the Eradication ofAntibiotics (Basel, Switzerland) · 2023
    Review
  7. Development of apigenin loaded gastroretentive microsponge for the targeting ofSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  8. Review
  9. Sitafloxacin for Third-LineJournal of clinical medicine · 2021
    Review
  10. The Potential Benefits of Vonoprazan asPharmaceuticals (Basel, Switzerland) · 2020
    Review
  11. Article
  12. Review
  13. Article
  14. Microarray-Based Detection and Clinical Evaluation forBioMed research international · 2018
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Toshihiro NishizawaDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.
Hidekazu Suzuki
Toshifumi Hibi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones show good oral absorption, no major side effects, and marked activity against H. pylori. Several authors have studied quinolone-based third-line therapy and reported encouraging results, with the reported H. pylori cure rates ranging from 60% to 84%. Resistance to quinolones is easily acquired, and the resistance rate is relatively high in countries with a high consumption rate of these drugs. We recently reported a significant difference in the eradication rate obtained between patients infected with gatifloxacin-susceptible and gatifloxacin-resistant H. pylori, suggesting that the selection of quinolones for third-line therapy should be based on the results of drug susceptibility testing. As other alternatives of third-line rescue therapies, rifabutin-based triple therapy, high-dose proton pump inhibitor/amoxicillin therapy and furazolidone-based therapy have been suggested.

Indexed as

Helicobacter pyloriquinolonethird-line therapy

Identifiers

PMID19308265
PMCPMC2654467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.