Evidence map›Paper›PMID 19307372›Full record

ArticleAntimicrobial agents and chemotherapy2009

Antifungal combinations against simulated Candida albicans endocardial vegetations.

Manjunath P Pai

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Antifungal Combinations againstJournal of fungi (Basel, Switzerland) · 2022
    Review
  3. Germs · 2020
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Manjunath P PaiCollege of Pharmacy, University of New Mexico, Albuquerque, New Mexico, USA. apai-icpd@OrdwayResearch.org
University of New Mexico · US

Funding

PHS HHS M01-0997
6 · The paper itself

Abstract

The in vitro effects of flucytosine (5FC), liposomal amphotericin B (L-AmB), and micafungin (Mica) combinations against two Candida albicans strains that simulated 24-hour-old endocardial vegetations were studied. Mica was superior to 5FC or L-AmB, and the 5FC-L-AmB-Mica combination was superior to all other treatments for one strain but no different from the dual combination of L-AmB-Mica for the other strain.

Indexed as

Amphotericin BAntifungal AgentsBiofilmsCandida albicansDrug CombinationsEchinocandinsEndocarditisFlucytosineHumansLipopeptidesMicafunginAmphotericin BAntifungal AgentsDrug CombinationsEchinocandinsFlucytosineLipopeptidesliposomal amphotericin BMicafungin

Identifiers

PMID19307372
PMCPMC2687236
OpenAlexW2130141234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.