Evidence map›Paper›PMID 19306773›Full record

ReviewCardiology clinics2009

New molecular imaging targets to characterize myocardial biology.

Alan R Morrison, Albert J Sinusas

Open access · greenAbstract readReview
In one paragraph

Review in Cardiology clinics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Direct myocardial ischemia imaging with exercise ¹⁸FDG.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2015
    Article
  2. Review
  3. Article
  4. PET and SPECT in cardiovascular molecular imaging.Nature reviews. Cardiology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alan R MorrisonYale University School of Medicine, Section of Cardiovascular Medicine, New Haven, CT 06520-8017, USA.
Albert J Sinusas
Yale University · US

Funding

Non-Invasive Methods for Imaging Myocardial AngiogenesisR01HL065662 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2001 to 2009
$3.2M
Imaging of MMP activation and myocardial strainsR01HL078650 · NHLBI · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2004 to 2007
$2.3M
DEDICATED ANIMAL SPECT X-RAY CT: NEUROSCIENCES10RR018039 · NCRR · YALE UNIVERSITY · PI SINUSAS, ALBERT J · 2004 to 2004
$500k
The Rac-2-induced macrophage proteome and vascular pathologyF32HL097422 · NHLBI · YALE UNIVERSITY · PI MORRISON, ALAN ROSS · 2009 to 2011
$168k
NCRR NIH HHS S10 RR018039NHLBI NIH HHS F32 HL097422NHLBI NIH HHS L30 HL115713NHLBI NIH HHS R01 HL065662NHLBI NIH HHS R01 HL078650
6 · The paper itself

Abstract

Molecular imaging represents a targeted approach to noninvasively assess biologic (both physiologic and pathologic) processes in vivo. Ideally the goal of molecular imaging is not just to provide diagnostic and prognostic information based on identification of the molecular events associated with a pathologic process but rather to guide individually tailored pharmacologic, cell-based, or genetic therapeutic regimens. This article reviews the recent advances in myocardial molecular imaging in the context of the cardiovascular processes of angiogenesis, apoptosis, inflammation, and ventricular remodeling. The focus is on radiotracer-based single photon emission computed tomography and positron emission tomography molecular imaging approaches.

Indexed as

ApoptosisDiagnosis, DifferentialHeart DiseasesHumansMyocardiumNeovascularization, PathologicPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonVentricular Remodeling

Identifiers

PMID19306773
PMCPMC2700784
OpenAlexW2103437173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.