Evidence map›Paper›PMID 19306771›Full record

ReviewCardiology clinics2009

Translation of myocardial metabolic imaging concepts into the clinics.

Adil Bashir, Robert J Gropler

Abstract readReview
In one paragraph

Review in Cardiology clinics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adil BashirDivision of Radiological Sciences, Cardiovascular Imaging Laboratory, Edward Mallinckrodt Institute of Radiology, St Louis, MO 63110, USA.
Robert J Gropler

Funding

ROLE OF ACE IN PULMONARY HYPERTENSIONP01HL013851 · NHLBI · WASHINGTON UNIVERSITY · PI WELCH, MICHAEL J. · 1985 to 2008
$16.7M
PET Quantification of Myocardial Substrate MetabolismR01HL069100 · NHLBI · WASHINGTON UNIVERSITY · PI GROPLER, ROBERT J · 2002 to 2006
$1.9M
NHLBI NIH HHS P01 HL013851NHLBI NIH HHS P0I-HL15851NHLBI NIH HHS R01 HL069100NIA NIH HHS AG15644PHS HHS R0I-HLE9100
6 · The paper itself

Abstract

Flexibility in myocardial substrate metabolism for energy production is fundamental to cardiac health. This loss in plasticity or flexibility leads to overdependence on the metabolism of an individual category of substrates, with the predominance in fatty acid metabolism characteristic of diabetic heart disease and the accelerated glucose use associated with pressure-overload left ventricular hypertrophy being prime examples. There is a strong demand for accurate noninvasive imaging approaches of myocardial substrate metabolism that can facilitate the crosstalk between the bench and the bedside, leading to improved patient management paradigms. In this article potential future applications of metabolic imaging, particularly radionuclide approaches, for assessment of cardiovascular disease are discussed.

Indexed as

Diagnosis, DifferentialFatty AcidsGlucoseHeart DiseasesHumansMagnetic Resonance SpectroscopyMyocardiumOxygen ConsumptionPositron-Emission TomographySeverity of Illness IndexTomography, Emission-Computed, Single-PhotonFatty AcidsGlucose

Identifiers

PMID19306771
PMCPMC2929683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.