Evidence map›Paper›PMID 19306601›Full record

ArticleHerpes : the journal of the IHMF2009

Cytomegalovirus vaccines: at last, a major step forward.

Mark R Schleiss

Abstract read
In one paragraph

Article in Herpes : the journal of the IHMF, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Cytomegalovirus: pathogen, paradigm, and puzzle.The Journal of clinical investigation · 2011
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mark R SchleissCenter for Infectious Diseases and Microbiology Translational Research, University of Minnesota Medical School, Minneapolis, MN 55455, USA. schleiss@umn.edu

Funding

Viral Immunomodulation and Rational CMV Vaccine DesignR01HD044864 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI GEBALLE, ADAM P., MCVOY, MICHAEL A · 2003 to 2015
$4.5M
VACCINES FOR PREVENTION OF EXPERIMENTAL CONGENITAL CMVR01HD038416 · NICHD · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SCHLEISS, MARK R. · 2000 to 2009
$2.2M
NICHD NIH HHS R01 HD038416NICHD NIH HHS R01 HD044864
6 · The paper itself

Abstract

Yow and Demmler published an editorial in 1992 entitled Congenital cytomegalovirus disease--20 years is long enough. This editorial pointed out that, despite the long-standing recognition of the major public health importance of congenital human cytomegalovirus (CMV) infection, few solutions had been forthcoming. In no area has the lack of progress been more frustrating than in the realm of CMV vaccine development. Although a number of vaccine strategies have been considered, few have advanced to the stage of efficacy testing.

Indexed as

Adjuvants, ImmunologicCytomegalovirusCytomegalovirus InfectionsCytomegalovirus VaccinesHumansVaccinationVaccines, AttenuatedVaccines, SubunitViral Envelope ProteinsAdjuvants, ImmunologicCytomegalovirus Vaccinesglycoprotein B, SimplexvirusVaccines, AttenuatedVaccines, SubunitViral Envelope Proteins

Identifiers

PMID19306601
PMCPMC4385584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.